Bulk 3,3'-Diindolylmethane (DIM) Powder Supplier in China
Wholesale bulk DIM powder for for Hormone Balance & Nutraceutical Formulations. Free sample, Wholesale price, Kosher, Halal, FDA-approved
- 99% pure DIM bulk powder (Tested by HPLC)
- Stable, Free-Flowing Powder for Easy Formulation
- Ideal for Hormone Balance & Estrogen Metabolism Support Products
- ISO-Certified Manufacturing & Strict Quality Control
- OEM Services: Capsules, Tablets, Custom Formulations
- Global Export Experience with Complete Documentation
Home / Products / Top Sellers / Wholesale 3,3′-Diindolylmethane (DIM) Powder
What is 3,3'-Diindolylmethane?
3,3′-Diindolylmethane, commonly referred to as DIM, is a natural compound formed during the digestion of indole-3-carbinol, found in cruciferous vegetables like broccoli, cabbage, and kale. It is widely recognized for its potential health benefits, including hormonal balance and support for healthy estrogen metabolism. The compound’s CAS number is 1968-05-4, and it is also known as diindolylmethane. Its molecular formula is C17H14N2, with a molecular weight of approximately 246.31 g/mol. DIM is typically available in white to light yellow crystalline powder form, with high purity levels of up to 98% in bulk specifications. Known for its moderate bioavailability, it is often combined with bioenhancers to improve absorption. Provita Biotech is a leading bulk supplier of 3,3′-Diindolylmethane Powder in China, providing premium quality for use in dietary supplements, nutraceuticals, and functional foods.
3,3'-Diindolylmethane (DIM) vs indole-3-carbinol (I3C)
3,3′-Diindolylmethane (DIM) and indole-3-carbinol (I3C) are bioactive compounds derived from cruciferous vegetables, each with distinct properties and benefits. While I3C is a precursor that converts into DIM in the stomach, DIM is more stable, potent, and bioavailable, making it a preferred choice for health supplements targeting hormonal balance and estrogen metabolism. I3C is less expensive but has a shorter half-life and lower stability, making it less effective unless rapidly converted to DIM. Below is a detailed comparison:
| Attribute | 3,3′-Diindolylmethane (DIM) | Indole-3-Carbinol (I3C) |
|---|---|---|
| CAS Number | 1968-05-4 | 700-06-1 |
| Other Names | Diindolylmethane | 1H-Indole-3-methanol |
| Molecular Formula | C17H14N2 | C9H9NO |
| Molecular Weight | 246.31 g/mol | 147.17 g/mol |
| Appearance | White to light yellow crystalline powder | White crystalline powder |
| Purity | Up to 98% | Up to 99% |
| Bioavailability | Moderate; can be enhanced with bioenhancers | Low; requires conversion to DIM in the stomach |
| Potency | Directly active | Indirect (must convert to DIM) |
| Half-Life | Longer (up to 4 hours) | Shorter (less than 1 hour) |
| Stability | High; does not degrade easily | Low; degrades rapidly in aqueous solutions |
| Popularity | High; widely used in supplements | Moderate; less preferred due to instability |
| Pricing | Higher; reflects higher stability and potency | Lower; less stable and potent |
| Mechanism | Directly supports estrogen metabolism | Precursor that converts into DIM |
| Applications | Dietary supplements, nutraceuticals | Limited use; mostly as a precursor to DIM |
| Botanical Sources | Cruciferous vegetables | Cruciferous vegetables |
3,3'-Diindolylmethane (DIM) COA
The Certificate of Analysis (COA) for 3,3′-Diindolylmethane (DIM) powder confirms a high purity level of 99.4% as determined by HPLC, surpassing the specification of 98.0% minimum. Heavy metals, including arsenic (As ≤ 0.0045 ppm), lead (Pb ≤ 0.06 ppm), cadmium (Cd ≤ 0.0043 ppm), and mercury (Hg ≤ 0.0042 ppm), are all within safe limits as per ICP/MS analysis, ensuring exceptional safety and quality. The residual solvents are absent or below detectable levels, meeting stringent USP standards. This showcases Provita Biotech’s commitment to delivering premium-quality DIM powder with superior safety and purity, making it a trusted supplier for bulk nutraceutical applications.
Application
Enhanced Athletic Performance
D-ribose is a naturally occurring sugar that plays a crucial role in energy production. As a supplement, D-ribose helps improve endurance, speed up recovery times, and reduce muscle fatigue. It supports ATP (adenosine triphosphate) synthesis, which is essential for muscle contraction during exercise. For athletes seeking improved performance and faster recovery, D-ribose is a valuable addition to their regimen.
Chronic Fatigue Syndrome
D-ribose has shown promising benefits in supporting individuals with chronic fatigue syndrome (CFS). By helping the body regenerate ATP, D-ribose can improve energy levels, reduce fatigue, and enhance overall well-being. It supports cellular energy metabolism, making it a natural choice for people battling fatigue-related conditions.
Cardiovascular Health
D-ribose is known to support heart health by aiding in ATP production, which is vital for heart muscle function. Studies suggest that D-ribose supplementation can improve the function of the heart, especially in individuals with cardiovascular issues. It can help enhance energy production in the heart muscle, leading to better overall cardiovascular health.
DIM powder Manufacturing Process
The manufacturing process of 3,3′-Diindolylmethane (DIM) powder, achieving 99% purity and conforming to international standards and third-party quality tests, involves the following steps:
Preparation of Reaction Mixture:
Indole is dissolved in a solvent mixture of methanol and water to create a homogeneous reaction medium.Addition of Formalin:
Formalin (formaldehyde solution) is gradually added to the reaction mixture. The reaction proceeds for one hour under controlled conditions.Cooling and Precipitation:
The reaction mixture is cooled, leading to the precipitation of crude 3,3′-Diindolylmethane.Washing and Purification:
The precipitate is thoroughly washed with water to remove impurities and by-products.Recrystallization:
The crude product is recrystallized twice using ethanol to enhance its purity and achieve the desired high-quality crystalline form.Drying:
The purified 3,3′-Diindolylmethane is dried under vacuum to remove residual solvents, ensuring a final product with a purity of 99%.
This process ensures the production of DIM powder that meets stringent international standards and third-party quality requirements, suitable for use in nutraceuticals, dietary supplements, and pharmaceutical formulations.
3,3'-Diindolylmethane Benefits
Hormonal Balance
DIM promotes healthy estrogen metabolism by supporting the production of beneficial estrogen metabolites while reducing harmful ones. This helps balance hormone levels in both men and women.Supports Women’s Health
DIM is widely used to alleviate symptoms of hormonal imbalance, such as PMS, menopausal discomfort, and irregular cycles, making it popular for women’s health.Men’s Hormonal Health
DIM aids in maintaining a healthy testosterone-to-estrogen balance, supporting prostate health, and promoting physical performance.Antioxidant Properties
DIM has antioxidant effects that help combat oxidative stress and protect cells from damage caused by free radicals.Supports Immune Function
By promoting a healthy inflammatory response, DIM contributes to a strong immune system.Weight Management
DIM is often included in weight management supplements due to its role in supporting fat metabolism and maintaining a healthy body composition.Skin Health
DIM may help in reducing skin issues like acne by regulating hormone levels and reducing inflammation.
These benefits make DIM a valuable addition to dietary supplements, promoting overall health and wellness.
Where to buy 3,3'-Diindolylmethane (DIM) bulk powder?
When sourcing high-quality 3,3′-Diindolylmethane (DIM) bulk powder, it’s essential to choose a reliable supplier that guarantees purity, safety, and compliance with international standards. ProVita Biotech stands out as a leading wholesale supplier in China, offering DIM powder with a purity of 99% for use in nutraceuticals, dietary supplements, and pharmaceutical formulations.
ProVita Biotech provides competitive pricing, third-party quality assurance, and flexible bulk quantities to meet your business needs. Whether you’re a manufacturer of health supplements or functional foods, ProVita Biotech ensures you receive premium-grade DIM powder with exceptional consistency.
For bulk purchases of DIM powder, trust ProVita Biotech, your expert partner in high-quality ingredients. Contact us today for a quote and elevate your product formulations with our top-notch 3,3′-Diindolylmethane.
FAQs
DIM powder is synthesized through a chemical reaction involving indole and formalin, followed by multiple purification steps to ensure high purity and compliance with international quality standards.
You can purchase high-quality DIM powder in bulk from ProVita Biotech, a trusted wholesale supplier in China. They offer 99% pure DIM powder with third-party quality certifications.
Yes, the sample is free of charge. You can use your own courier account to arrange for collection, or we can ship it for you with the freight cost covered on your side. Additionally, the shipping cost will be deducted from your bulk order payment.
We generally do not have a strict Minimum Order Quantity (MOQ) requirement. Our standard packaging is 25kg per drum, making 25kg an ideal starting point. Smaller quantities, such as 10kg or other amounts, are also available, but please note that the unit cost may increase slightly for smaller orders. Feel free to contact us to discuss your specific requirements.
Yes, we have branches and warehouses in key locations worldwide: California (USA), Paris (Europe), Singapore (Asia), Shanghai (China), and Chestiville (Australia).