Bulk Alpha Ketoglutaric Acid
Trusted Supplier for Longevity & Healthy Aging Solutions with high-purity AKG powders, capsules, tablets, OEM services
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What is Alpha Ketoglutaric Acid?
Alpha Ketoglutaric Acid (AKG, also known as 2-Oxoglutaric Acid, α-Ketoglutarate) is a pure and highly bioavailable compound that plays a central role in cellular energy production and metabolic balance, making it a key ingredient in longevity and anti-aging formulations. With the molecular formula C5H6O5 and a molecular weight of 146.1 g/mol, AKG is recognized under CAS No. 328-50-7. Naturally found in plants and botanical sources such as spinach, beets, and certain fruits, Alpha Ketoglutaric Acid is commonly manufactured into supplement-grade raw material for health applications. ProVita Biotech supplies high-quality bulk Alpha Ketoglutaric Acid powder with a purity of 98%, presented as a fine white crystalline powder with excellent bioavailability. Standard bulk packaging is 25kg/drum, and specifications are laboratory-tested to ensure safety and consistency. As the leading bulk Alpha Ketoglutaric Acid supplier in China, ProVita Biotech also provides CA-AKG raw materials and offers OEM services including capsules, tablets, private label solutions, and custom packaging to meet the needs of global supplement brands and nutraceutical companies.
Alpha Ketoglutaric Acid VS CA AKG
Both Alpha Ketoglutaric Acid (AKG) and Calcium Alpha-Ketoglutarate (CA-AKG) are recognized for their roles in healthy aging, cellular energy, and longevity support. However, CA-AKG generally offers greater stability, slower release, and higher potency for longevity supplements, making it more popular in anti-aging formulations. AKG, on the other hand, is the direct, pure form and is still favored by certain supplement brands due to its lower cost, simpler formulation, and flexibility in blending with other compounds.
| Feature | Alpha Ketoglutaric Acid (AKG) | Calcium Alpha-Ketoglutarate (CA-AKG) |
|---|---|---|
| CAS Number | 328-50-7 | 71686-01-6 |
| Other Names | 2-Oxoglutaric Acid, α-Ketoglutarate | Calcium 2-Oxoglutarate, Calcium AKG |
| Molecular Formula | C5H6O5 | C10H14CaO10 |
| Molecular Weight | 146.1 g/mol | ~334.3 g/mol |
| Appearance | Fine white crystalline powder | White crystalline powder |
| Food Sources | Naturally found in spinach, beets, grapes, some fruits | Derived from AKG bound with calcium; not naturally occurring |
| Specifications | 98% purity bulk powder | 98% purity bulk powder |
| Purity | ≥98% | ≥98% |
| Bioavailability | High, but shorter half-life | Sustained release, better retention |
| Potency | Effective, but less stable in body | Higher potency for longevity use |
| Dosage (common range) | 1–3 g/day | 500 mg–2 g/day |
| Half-life in body | Shorter (~1–2 hours) | Longer (~4–6 hours) |
| Stability | Less stable, degrades faster | More stable with calcium salt form |
| Popularity | Widely used in sports nutrition and general supplements | Increasingly popular in longevity and anti-aging supplements |
| Pricing | Generally lower, cost-effective | Higher price range due to processing & demand |
| Main Benefits | Cellular energy, sports recovery, detox support | Longevity, bone health, anti-aging, mitochondrial function |
| Packaging | 25kg/drum (bulk) | 25kg/drum (bulk) |
| OEM Options | Capsules, tablets, blends | Capsules, tablets, private label, custom formulations |
Alpha Ketoglutaric Acid Certificate of Analysis(COA)
ProVita Biotech’s Alpha Ketoglutaric Acid (AKG) Powder 98% is manufactured under strict quality control, with a Certificate of Analysis confirming an assay of ≥98% purity (tested at 100.0%), heavy metals ≤10ppm, and residual solvents meeting international safety limits. The product is supplied in 25kg/drum, double-sealed with food-grade polyethylene inner bags to ensure stability and safety. Recommended storage is in a cool, dry, and well-ventilated place, away from heat and oxidizing agents. Certified with Halal, Kosher, ISO9001, ISO20000, and Intertek standards, our AKG ingredient is tested for microbial safety and complies with global regulations. This ensures supplement manufacturers, nutraceutical brands, and distributors receive only high-quality, safe, and reliable AKG raw materials. At ProVita Biotech, we care deeply about product quality and safety, offering ingredients that meet international standards and third-party validation for use in capsules, tablets, and custom formulations.
Application
Longevity Supplements
Alpha Ketoglutaric Acid is widely used in anti-aging and longevity formulations due to its role in cellular energy and mitochondrial health. It helps support metabolic balance, reduce oxidative stress, and promote healthy lifespan, making it a key ingredient in premium nutraceuticals.
Bone & Joint Health
AKG is increasingly applied in bone and joint health supplements, as research shows it supports calcium metabolism and collagen synthesis. This makes it beneficial for maintaining strong bones, reducing age-related bone loss, and improving overall skeletal health.
Sports Nutrition & Recovery
In the sports industry, Alpha Ketoglutaric Acid is valued for enhancing muscle recovery and performance. By aiding nitrogen balance and energy metabolism, AKG helps athletes reduce fatigue, improve endurance, and accelerate post-workout recovery.
Alpha Ketoglutaric Acid Manufacturing Process
At ProVita Biotech, Alpha Ketoglutaric Acid (AKG) Powder 98% is produced using a controlled and standardized process to ensure high purity, safety, and international compliance. The process begins with sodium hydrogen glutamate as the raw material, which undergoes a conversion step to form the desired intermediate. This is followed by purification to remove impurities and enhance product quality. The solution is then concentrated to achieve the proper consistency before undergoing crystallization and centrifugation, which ensures the formation of fine crystalline powder. After crystallization, the material is carefully dried to achieve optimal stability, then mixed and sub-packaged under GMP conditions. A critical metal detection (CCP1) step ensures safety and compliance with global heavy metal limits. Finally, the finished product is packaged in 25kg drums and moved to storage under controlled conditions.
The resulting Alpha Ketoglutaric Acid powder (98% assay) is a pure, fine white crystalline powder that passes strict international standards and third-party quality tests. Certified with Halal, Kosher, ISO9001, ISO20000, and Intertek, ProVita Biotech guarantees that every batch meets the needs of global supplement manufacturers, nutraceutical brands, and distributors.
Alpha Ketoglutaric Acid Benefits
- Healthy aging & longevity: Alpha Ketoglutaric Acid (AKG) supports cellular energy and metabolic balance for healthy aging.
- Mitochondrial function: Drives the Krebs cycle to promote efficient ATP production and vitality.
- Bone & joint support: Assists collagen synthesis and calcium metabolism to help maintain strong bones.
- Nitrogen/ammonia balance: Aids detox pathways to clear ammonia and support recovery.
- Exercise performance & recovery: Supports endurance, helps reduce fatigue, and speeds post-workout recovery.
- Antioxidant defense: Helps reduce oxidative stress for better cellular resilience.
- Metabolic health: Supports amino acid metabolism and healthy energy utilization.
- Immune support: Promotes cellular processes important for immune function.
- Formulation versatility: Ideal for capsules, tablets, and blends; pairs well with Calcium AKG.
- High-purity, bioavailable: 98% AKG powder with excellent bioavailability for premium supplements.
Where to buy bulk Alpha Ketoglutaric Acid Powder?
ProVita Biotech Co., Ltd. is the leading Alpha Ketoglutaric Acid supplier in China, delivering high-purity bulk AKG powder (≥99%) at competitive wholesale pricing direct from our China-based factory. As a trusted bulk ingredient manufacturer, we ensure strict quality control with every batch, backed by COA, MSDS, GMP, ISO, Kosher, and Halal certificates.
Our bulk Alpha Ketoglutaric Acid powder is laboratory-tested and verified through third-party testing, guaranteeing safety, consistency, and international compliance. We provide OEM services including customized capsules, tablets, and private label blends, with flexible packaging solutions tailored to your brand.
With stable production capacity and global export experience, ProVita Biotech supports supplement brands, nutraceutical contract manufacturers, and distributors worldwide. We also offer free samples to verify quality before bulk purchase.
Choose ProVita Biotech for high quality Alpha Ketoglutaric Acid at the best factory price, and your reliable partner for bulk, wholesale, and OEM solutions.
FAQs
AKG is the pure form of Alpha Ketoglutaric Acid, widely used in healthy aging and longevity supplements. AAKG is a bonded form of arginine and AKG, commonly used in sports nutrition to support nitric oxide production. The best choice depends on your target market—longevity brands usually prefer AKG, while sports formulas often use AAKG.
Common forms include Alpha Ketoglutaric Acid (AKG), Calcium Alpha-Ketoglutarate (Ca-AKG), and Arginine Alpha-Ketoglutarate (AAKG). Among them, Ca-AKG is often preferred for longevity due to its stability and sustained release, while pure AKG is cost-effective and versatile for broad formulations.
Our AKG powder is produced through a controlled conversion, purification, crystallization, drying, and packaging process with strict GMP compliance. Every batch undergoes metal detection and third-party quality testing to ensure ≥98% purity.
Our Alpha Ketoglutaric Acid is certified with Halal, Kosher, GMP, ISO9001, ISO20000, and Intertek. Certificates of Analysis (COA) and MSDS are provided for every batch.
The MOQ is typically 25kg (1 drum). Standard lead time is 7-15 working days depending on order size and shipping destination.
Yes. ProVita Biotech offers OEM and private label services, including capsules, tablets, blends, and custom packaging solutions, tailored for supplement brands and distributors.
AKG has been studied for its role in supporting nitrogen balance and detoxification, which may indirectly benefit kidney health. However, supplement brands should avoid medical claims and instead highlight its metabolic and cellular support functions.
AAKG may provide more sustained nitric oxide benefits than standalone L-Arginine, making it a popular choice in pre-workout supplements. For healthy aging and longevity markets, pure AKG or Ca-AKG is more suitable.
Popular combinations include Nicotinamide Mononucleotide (NMN), Urolithin A, Collagen, Magnesium, Creatine, and Arginine depending on the formulation goals, like anti-aging, sports performance, or cellular energy.