Bulk Caffeine Anhydrous Powder Supplier in China
Wholesale bulk caffeine anhydrous for Pre-workout, sports nutrition supplements, Fat burner and weight management products. Free sample, Wholesale price, Kosher, Halal, FDA-approved
- 99.9% pure caffeine anhydrous, white crystalline powder
- Meets EP10.0, USP2021, BP2022, FCC12, and CP2020 standards
- Natural and synthetic caffeine anhydrous available in bulk
- Annual export volume over 5000 tons with stable long-term supply
- OEM services for capsules, tablets, powders, and custom formulations
- Bulk packaging in 25kg drums, cartons, supersacks, or custom options
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What is Caffeine Anhydrous?
Caffeine anhydrous is a highly purified, water-free form of caffeine that can be produced from natural botanical or food sources such as coffee beans, tea leaves, and cocoa beans, or through controlled chemical synthesis. Both natural and synthetic sources produce the same standardized caffeine molecule used by supplement companies, nutrition brands, contract manufacturers, distributors, and importers. Caffeine anhydrous is also referred to as anhydrous caffeine, natural caffeine anhydrous, or synthetic caffeine anhydrous, with CAS number 58-08-2, molecular formula C₈H₁₀N₄O₂, and molecular weight 194.19. It is manufactured to a minimum 99 percent purity by HPLC and appears as a white crystalline powder with good solubility in water, especially warm water, providing high bioavailability and precise dosing without sugar or unnecessary additives found in coffee or energy drinks. Anhydrous caffeine is commonly supplied as a powdered caffeine ingredient for beverages, energy supplements, sports nutrition products, dietary supplements, and over-the-counter stimulant formulations, and is traded internationally under the caffeine anhydrous HS code. Standard bulk packaging includes 25kg drums, 25kg cartons, 20kg cartons, and 500kg supersacks, with custom bulk packaging available. The ingredient meets EP10.0, USP2021, BP2022, FCC12, and CP2020 standards. ProVita Biotech supplies both natural and synthetic caffeine anhydrous powder in bulk and also offers OEM services for capsules, tablets, powders, and custom formulations for supplement brands, contract manufacturers, distributors, and importers worldwide.
Caffeine Anhydrous vs Caffeine
For supplements, sports nutrition, and functional products, caffeine anhydrous is generally the better choice. It offers higher purity, stronger potency per gram, better stability, longer shelf life, and more precise dosing compared with regular caffeine from beverages or extracts. Standard caffeine from coffee or tea is more suitable for direct consumption as drinks, while caffeine anhydrous is preferred for capsules, tablets, powders, and beverage premixes. This is why caffeine anhydrous is far more popular in commercial supplement manufacturing.
| Item | Caffeine Anhydrous | Caffeine (Regular / Natural Caffeine) |
|---|---|---|
| Definition | Water-free, concentrated caffeine in purified powder form | Caffeine naturally present in coffee, tea, cocoa, or beverages |
| CAS Number | 58-08-2 | 58-08-2 |
| Other Names | Anhydrous caffeine, natural caffeine anhydrous, synthetic caffeine anhydrous | Natural caffeine, coffee caffeine, tea caffeine |
| Molecular Formula | C₈H₁₀N₄O₂ | C₈H₁₀N₄O₂ |
| Molecular Weight | 194.19 | 194.19 |
| Appearance | White crystalline powder | Brown liquid (coffee, tea) or crude powder in extracts |
| Food / Botanical Sources | Natural types extracted from Coffee Arabica seeds or produced synthetically | Coffee beans, tea leaves, cocoa beans, guarana |
| Types | Natural caffeine anhydrous and synthetic caffeine anhydrous | Brewed caffeine or plant extracts |
| Specifications | EP, USP, BP, FCC, CP compliant | No standardized pharmacopeia specs in beverages |
| Typical Purity | 99%-99.9% by HPLC | Highly variable depending on source |
| Bioavailability | High and fast absorption | High, but slower and variable due to other compounds |
| Potency | Very high concentration | Much lower per serving |
| Dosage Accuracy | Extremely precise | Difficult to control |
| Example Equivalency | 100 mg caffeine anhydrous ≈ 1 strong coffee | One cup of coffee ≈ 80-100 mg caffeine |
| Safety Note | FDA warns small amounts are extremely potent | Lower risk due to dilution in drinks |
| Half-Life | About 5-7 hours | About 5-7 hours |
| Stability | Very stable, long shelf life | Lower stability in liquid form |
| Shelf Life | 36-60 months under proper storage | Short, depends on beverage or extract |
| Popularity in Supplements | Very high | Low |
| Popularity in Beverages | Medium | Very high |
| Pricing Range (Bulk) | Lower cost per mg due to high potency | Higher cost per effective caffeine unit |
| Main Benefits | Strong stimulation, precise dosing, easy formulation | Natural perception, familiar source |
| Main Uses | Supplements, pre-workouts, energy powders, tablets, capsules | Coffee, tea, energy drinks |
| Regulatory Acceptance | Widely accepted for supplements | Accepted mainly as food and beverage ingredient |
According to the U.S. Food and Drug Administration, one teaspoon of pure caffeine powder is roughly equivalent to about 28 cups of coffee, highlighting why caffeine anhydrous must be handled and dosed carefully in manufacturing environments.
- Choose caffeine anhydrous for supplements, capsules, tablets, powders, and beverage premixes
- Choose regular caffeine mainly for direct consumption in coffee or tea
- For commercial formulations, caffeine anhydrous offers better consistency, stability, pricing efficiency, and scalability
Caffeine Anhydrous Certificate of Analysis(COA)
ProVita Biotech’s Certificate of Analysis for caffeine anhydrous powder demonstrates consistent quality and safety for supplement manufacturers and distributors. Each batch is tested using HPLC methods, with an assay of 98.5-101.0% caffeine, and typical commercial lots reaching 99.0-99.9% purity. Moisture is strictly controlled at ≤0.5%, sulphated ash at ≤0.1%, and total impurities at ≤0.1%, ensuring a highly refined and stable caffeine ingredient. Heavy metals meet international limits, with total heavy metals ≤10 ppm and lead ≤1 mg/kg. Residual solvents are tightly monitored, including chloroform residue ≤60 ppm when applicable. Additional quality indicators include a melting point of 235-238°C and sulphates ≤500 ppm, with microbiological parameters controlled according to pharmacopeia requirements when required. The product is manufactured and released in compliance with EP, USP, BP, FCC, and CP standards, and supplied in 25kg drums, 25kg cartons, 20kg cartons, or 500kg supersacks, with a shelf life of up to 60 months under proper storage conditions. Supported by in-house quality control and third-party testing where required, ProVita Biotech places strong emphasis on product quality and safety, delivering reliable caffeine anhydrous powder for global supplement manufacturers and distributors
Application
Dietary Supplements and Sports Nutrition
Caffeine anhydrous is widely used in dietary supplements, pre-workout formulas, fat burners, and sports nutrition products due to its high concentration and rapid bioavailability. Its stable white crystalline powder form allows accurate dosing in capsules, tablets, and powders, helping supplement companies deliver consistent stimulant performance and energy support.
Functional Beverages and Energy Drinks
In functional beverages and energy drink formulations, caffeine anhydrous serves as a reliable caffeine additive that dissolves easily and provides controlled caffeine levels without adding sugar or unwanted flavors. It is commonly used in energy drink powders, instant beverage mixes, and ready-to-drink products where precise caffeine content and clean labeling are important.
Pharmaceutical and OTC Products
Caffeine anhydrous is also used in pharmaceutical and over-the-counter products, including stimulant medications and combination pain relief formulas. Its standardized purity, stability, and compliance with pharmacopeia standards make it suitable for pharmaceutical manufacturing where consistent quality and regulatory acceptance are required.
Caffeine Anhydrous Manufacturing Process
ProVita Biotech’s caffeine anhydrous powder 99% manufacturing process is conducted under controlled GMP and HACCP conditions to ensure high purity, safety, and consistent quality. According to the caffeine manufacture flow chart, production starts with raw material preparation, followed by condensation and cyclization reactions to form the caffeine core structure. The process then continues through nitrosation and hydrogenation reduction, which are precisely controlled to obtain the correct molecular structure. A methylation step is applied to complete the caffeine molecule, followed by closed-loop processing and acylation control to improve reaction efficiency and stability.
After synthesis, the material undergoes primary purification and secondary purification to remove residual reactants and process impurities. The purified product is then processed through centrifugation, granulating, and sieving to achieve uniform particle size and consistent physical properties. Controlled drying and crushing steps produce the final white crystalline caffeine anhydrous powder. A metal detection step is applied as a critical control point to prevent metal contamination before the product is released as finished caffeine anhydrous powder .
The final caffeine anhydrous powder reaches 99% or higher purity, confirmed by HPLC testing, with strict limits on moisture, impurities, heavy metals, and residual solvents. Each batch is evaluated according to international standards including EP, USP, BP, FCC, and CP, and is supported by third-party quality testing when required. Through multi-stage purification, HACCP monitoring, and batch-by-batch quality control, ProVita Biotech ensures its caffeine anhydrous powder meets global regulatory requirements and delivers reliable quality and safety for supplement manufacturers, contract manufacturers, distributors, and importers worldwide.
Caffeine Anhydrous Benefits
- Provides fast-acting energy and alertness due to high bioavailability
- Delivers precise and consistent caffeine dosing for formulations
- Supports physical performance and endurance in sports nutrition products
- Enhances focus, concentration, and mental alertness
- Offers high potency with smaller dosage compared to regular caffeine sources
- Dissolves easily in water, especially warm water, for flexible applications
- Stable white crystalline powder with long shelf life
- Suitable for capsules, tablets, powders, and beverage mixes
- Free from sugar, calories, and unnecessary additives
- Widely accepted for use in supplements, functional beverages, and pharmaceutical products
Where to buy bulk Caffeine Anhydrous?
If you are looking for reliable caffeine anhydrous manufacturers or caffeine anhydrous suppliers in China, ProVita Biotech Co., Ltd. is a trusted factory supplier specializing in high quality caffeine anhydrous for global markets. We supply bulk caffeine anhydrous powder directly from China with competitive wholesale pricing, stable supply, and full regulatory documentation for supplement companies, brands, contract manufacturers, distributors, and importers.
ProVita Biotech offers 99.9 USP-grade anhydrous caffeine for sale, compliant with caffeine anhydrous USP standards and supported by complete caffeine anhydrous MSDS, COA, and third-party testing reports. Our caffeine anhydrous is produced under GMP conditions and is available with Kosher, Halal, and other certificates upon request. Bulk packaging options include 25kg per drum, 25kg per carton, 20kg per carton, and 500kg supersack, with flexible quantities such as 10 kg anhydrous caffeine also available for trial orders.
We supply bulk caffeine anhydrous powder with multiple particle size options including 20 mesh, 40 mesh, 80 mesh, custom meshes, and micronized caffeine anhydrous to meet different formulation needs. In addition to raw material supply, ProVita Biotech provides OEM services for capsules, tablets, powders, and customized formulations, including anhydrous caffeine tablets and other finished dosage forms. Caffeine anhydrous liquid solutions can also be discussed for specific applications.
As a direct China factory supplier, we offer transparent bulk caffeine anhydrous price per kg, factory-direct wholesale terms, free samples for evaluation, and professional export support. Contact ProVita Biotech today to source high quality caffeine anhydrous powder in bulk with reliable quality, competitive pricing, and long-term supply assurance.
FAQs
Yes, caffeine anhydrous and caffeine have the same chemical structure and CAS number 58-08-2. The difference is that caffeine anhydrous is a purified, water-free form designed for industrial use.
Caffeine anhydrous is not chemically stronger than caffeine, but it is more concentrated by weight because it contains no water. This allows more caffeine per gram and more precise dosing in supplements compared with caffeine from beverages or extracts.
Caffeine anhydrous can be natural or synthetic. Natural caffeine anhydrous is extracted from botanical sources such as Coffee Arabica seeds, while synthetic caffeine anhydrous is produced by chemical synthesis. Both forms are chemically identical and meet pharmacopeia standards.
Caffeine anhydrous BP or USP refers to caffeine anhydrous that complies with British Pharmacopoeia or United States Pharmacopeia standards. ProVita Biotech supplies caffeine anhydrous that meets BP, USP, EP, FCC, and CP requirements.
For finished products, safe intake depends on formulation and regulatory guidelines in the target market. From a manufacturing perspective, precise dosing is critical because caffeine anhydrous is highly concentrated. Product developers should follow FDA or EFSA guidance for finished dosage levels.
Most supplements are formulated at 100 to 200 mg per serving, depending on application. Final dosage decisions should follow local regulations and product positioning.
Yes, caffeine anhydrous is widely used in beverage premixes, energy drinks, and functional beverages due to its solubility and controlled caffeine content.
Caffeine citrate contains water and citric acid, resulting in lower caffeine concentration per gram. Caffeine anhydrous is more concentrated and commonly used in supplements.
Dicaffeine malate is a buffered form that releases caffeine more slowly. Caffeine anhydrous provides faster absorption and is preferred when immediate stimulant effect is required.
Caffeine anhydrous offers a fixed and measurable caffeine ratio, while natural extracts vary depending on source and processing.
Green coffee bean extract contains caffeine plus other plant compounds, while caffeine anhydrous is pure caffeine with predictable potency and dosing.
Caffeine anhydrous is produced either by extraction from natural sources or by chemical synthesis, followed by purification, crystallization, drying, and quality testing under GMP and HACCP systems.
Caffeine anhydrous typically has a shelf life of 36 to 60 months when stored in sealed packaging under cool, dry conditions.
Yes. Available options include 20 mesh, 40 mesh, 80 mesh, micronized caffeine anhydrous, and custom particle sizes.
Yes. ProVita Biotech provides OEM services including capsules, tablets, powders, and customized formulations containing caffeine anhydrous.
We provide COA, MSDS, specification sheets, and third-party testing reports. GMP, Kosher, Halal, and other certificates are available upon request.