Bulk Creatine Alpha-Ketoglutarate Powder Supplier in China
Pure Creatine AKG 2:1 Ingredient for Pre Workout Pump, Wholesale price, Kosher, Halal, FDA-approved
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What is Creatine Alpha-Ketoglutarate Chelate?
Creatine Alpha-Ketoglutarate (Creatine AKG) is a stable compound created by combining creatine with alpha-ketoglutaric acid to improve creatine absorption, ATP production, endurance, and overall muscle performance. It is not found in botanical or food sources, and is produced through controlled chemical synthesis to achieve high purity grades such as 99% HPLC, with both 2:1 (Creatine to AKG) and 1:1 ratios available. Creatine AKG appears as a white crystalline powder, dissolves well in water, and provides enhanced bioavailability compared to traditional creatine forms due to better transport efficiency and digestive tolerance. The molecular formula and molecular weight vary by ratio, but common chemical listings for the 1:1 form reference C9H15N3O7 with a molecular weight of about 277.23 g/mol, while the 2:1 form has a higher theoretical molecular weight in the 406–415 g/mol range. Because different ratios exist in the market, several CAS numbers may apply: 5256-76-8, which is the most widely used commercial CAS for Creatine AKG; 315669-78-4, which is commonly listed in chemical databases for the 1:1 form; and 9009-62-5, which is used by some suppliers for the 2:1 grade. No single CAS number is universally assigned to the 2:1 structure, so suppliers typically reference one or more of these options. Other common names include Creatine AKG, Creatine Alpha Ketoglutarate, Creatine AKG 2:1, and Creatine AKG 1:1. As a leading bulk Creatine AKG supplier in China, ProVita Biotech provides high purity Creatine AKG powder in 25 kg drums and offers OEM services including capsules, tablets, blends, and custom formulations.
Creatine alpha ketoglutarate vs Monohydrate
The difference between Creatine Alpha-Ketoglutarate (Creatine AKG) and Creatine Monohydrate mainly lies in absorption, digestive comfort, and formulation goals. Creatine Monohydrate remains the most researched, most popular, and most economical option, making it the standard choice for general muscle strength and athletic performance. Creatine Alpha-Ketoglutarate, on the other hand, offers potentially better bioavailability, smoother digestion, less water retention, and improved nutrient transport due to the AKG component, making it preferred in premium pre-workout formulas. For cost-effectiveness and proven results, monohydrate wins. For faster absorption, better solubility, and high-end performance blends, Creatine AKG may be the better fit.
| Item | Creatine Alpha-Ketoglutarate (AKG) | Creatine Monohydrate |
|---|---|---|
| CAS Number | Multiple CAS numbers depending on ratio: 5256-76-8 (common trade CAS), 315669-78-4 (chemical database CAS for 1:1), 9009-62-5 (used by some suppliers for 2:1) | 6020-87-7 (official CAS) |
| Other Names | Creatine AKG, Creatine Alpha Ketoglutarate 2:1 or 1:1, Creatine-AKG | Creatine Mono, CM, Creatine Hydrate |
| Appearance | White crystalline powder | White crystalline powder |
| Food Sources | None (synthetic compound) | Trace amounts in meat and fish |
| Specifications | 99% HPLC, available in 2:1 and 1:1 ratios | 99% purity typical, micronized and regular grades |
| Purity | 99% HPLC | 99% (commonly 99.5%+) |
| Bioavailability | Higher than monohydrate due to AKG-enhanced transport | Good, well studied but slightly lower than AKG |
| Potency | Strong performance benefits with potentially faster uptake | Highly effective with extensive scientific evidence |
| Dosage | 1.5–3 g/day (often lower due to enhanced absorption) | 3–5 g/day standard |
| Half-Life | Estimated 3–5 hours | 3–4 hours |
| Stability | Stable, less risk of converting to creatinine in solution | Highly stable in dry form but less stable in liquid |
| Popularity | Popular in premium pre-workouts | Most popular creatine worldwide |
| Pricing | Higher price range; varies widely by ratio and purity | Lowest cost; very budget friendly |
| Main Benefits | Better absorption, less bloating, reduced digestive stress, improved nutrient transport, enhanced ATP support | Strong evidence for muscle strength, power, endurance, cell volumization |
| Solubility | Good water solubility | Moderate solubility; improved when micronized |
| Water Retention | Typically lower | More noticeable in some users |
| Use in Formulations | Premium pre-workouts, advanced blends | Mass-market supplements, basic creatine powders |
| Best For | Athletes wanting faster uptake and less stomach discomfort | General users, beginners, cost-effective performance |
Creatine AKG Certificate of Analysis(COA)
ProVita Biotech’s Creatine Alpha-Ketoglutarate 2:1 is manufactured under strict ISO9001 and ISO22000 quality systems, and each batch undergoes comprehensive testing to ensure purity, safety, and compliance with global standards. According to the latest Certificate of Analysis, the product delivers an assay of 99.5% (specification: not less than 98.0%), with creatine content at 66.2% and alpha-ketoglutarate at 33.3%, fully aligning with the 2:1 ratio requirement. Heavy metals meet stringent limits, including Lead <3 ppm, Arsenic <1.0 ppm, Cadmium <1.0 ppm, and Mercury <0.1 ppm, with all results conforming. The powder demonstrates excellent stability with loss on drying at 0.45% and residue on ignition at only 0.02%. Microbiological safety is verified through third-party methods, showing TPC <1000 cfu/g, yeast & mold <100 cfu/g, and Salmonella and Coliforms negative per 10 g, ensuring suitability for dietary supplement manufacturing. The product is a white powder, 100% passing 40 mesh, and packed in 25 kg drums with double polyethylene inner liners to protect against moisture, oxidation, and contamination. All parameters conform to ProVita Biotech’s in-house standards and international safety expectations, reflecting our commitment to delivering high-purity, low-contaminant, and reliable Creatine AKG powder for supplement manufacturers and global distributors who prioritize quality and consumer safety.
Application
Pre-Workout Supplements
Creatine AKG is widely used in pre-workout formulas for its enhanced absorption and ability to boost ATP production, strength, energy, and endurance. The AKG component supports efficient nutrient delivery, making it ideal for athletes seeking fast uptake and reduced digestive discomfort compared to monohydrate.
Muscle-Building and Performance Products
As a premium ergogenic ingredient, Creatine AKG supports lean muscle growth, power output, and training performance. Its high bioavailability and reduced bloating make it popular in advanced bodybuilding blends, strength boosters, and sports nutrition powders designed for high-intensity training.
Recovery and Post-Workout Formulas
Creatine AKG is used in post-workout recovery supplements to replenish ATP, support muscle repair, reduce fatigue, and improve recovery time. The AKG molecule aids cellular energy cycles, helping athletes recover faster and maintain consistent training performance.
Creatine AKG Manufacturing Process
ProVita Biotech’s Creatine Alpha-Ketoglutarate 2:1 manufacturing process follows a controlled, GMP-compliant production flow designed to ensure high purity, safety, and batch-to-batch consistency. The process begins by adding pure water into a reaction still and gradually heating it. Alpha-ketoglutaric acid is introduced first, followed by continuous stirring to ensure complete dissolution and activation. Once the solution reaches the ideal reaction conditions, creatine is added in the precise 2:1 ratio. The mixture undergoes a controlled reaction phase of 4–5 hours, during which temperature, pH, and mixing speed are carefully monitored. After the reaction is complete, the temperature is lowered to stabilize the newly formed Creatine AKG complex. The mixture then proceeds to centrifugation, where impurities and non-reacted materials are removed. Ethanol absolute is used during this stage to aid purification and crystallization. The purified product is then transferred to the drying stage and processed into a stable, free-flowing powder before being packed into 25 kg drums with food-grade liners. The final Creatine Alpha-Ketoglutarate 2:1 powder produced by ProVita Biotech reaches 99% purity, meets international quality standards, and successfully passes third-party microbiological, heavy metal, and purity testing, ensuring a premium ingredient suitable for global supplement manufacturers and distributors.
Creatine AKG Benefits
- Supports faster ATP regeneration for improved strength and power output
- Enhances muscle performance during high-intensity training
- Provides higher bioavailability compared to creatine monohydrate
- Reduces bloating and digestive discomfort for smoother absorption
- Promotes better nutrient delivery through AKG-enhanced transport
- Helps increase lean muscle mass and training volume
- Improves endurance and workout stamina
- Aids post-workout recovery and reduces muscle fatigue
- Supports cellular energy cycles through the alpha-ketoglutarate pathway
- Offers superior solubility and mixing for premium supplement formulations
- Ideal for pre-workout, bodybuilding, and performance nutrition products
Where to buy bulk Creatine AKG Powder?
Looking for a reliable source of bulk Creatine Alpha-Ketoglutarate (AKG) powder? ProVita Biotech Co., Ltd. is a leading China factory and supplier specializing in high-purity Creatine AKG, produced under strict GMP standards with full Kosher, Halal, and third-party testing certificates. Our Creatine AKG is a novel blend of creatine and alpha-ketoglutarate and is widely recognized as one of the most stable and bioavailable creatine compounds in sports nutrition. Due to increasing global demand, stock for this ingredient is often limited, and bulk orders frequently sell out quickly. ProVita Biotech offers OEM services for capsules, tablets, blends, and premixes, along with wholesale pricing, free samples, and fast international shipment. If you are a supplement brand, distributor, or manufacturer searching for a trusted partner for bulk Creatine AKG powder, ProVita Biotech delivers consistent quality, competitive pricing, and dependable supply from a certified factory in China.
FAQs
Creatine Alpha-Ketoglutarate (AKG) is considered one of the most bioavailable and stable creatine forms, ideal for high-end pre-workout, muscle-building, and performance formulas.
Creatine AKG is not a true chelate, but it offers higher absorption, better stability, and less water retention than monohydrate, making it preferred for advanced formulations.
Yes. AAKG (Arginine Alpha-Ketoglutarate) and Creatine AKG are commonly used together in pre-workout blends to support nitric oxide, strength, and cellular energy.
Creatine AKG is often chosen by brands seeking a gentler creatine form with reduced bloating, smoother digestion, and no subcutaneous water retention.
Creatine monohydrate may temporarily raise creatinine in some users, while Creatine AKG offers improved stability and reduced conversion to creatinine in stomach acid.
Our Creatine Alpha-Ketoglutarate 2:1 powder is 99% HPLC-tested purity, with low heavy metals, clean microbiology, and full third-party verification.
Creatine and alpha-ketoglutaric acid are dissolved, reacted under controlled temperature and pH, purified through centrifugation with ethanol, dried, and processed into a high-purity crystalline powder.
Our standard MOQ is 25 kg (one drum), with lower trial quantities available for testing and formulation R&D.
Regular stock ships within 3–5 days. Large orders or OEM production typically require 1–2 weeks depending on quantity.
Yes. We offer OEM capsules, tablets, blends, premixes, and custom packaging for supplement brands.
Bulk orders are packed in 25 kg fiber drums with double food-grade liners for stability and safety during transport.
We ship globally by air, sea, or express courier, with full export documentation including COA, customs declaration, and safety certificates.
As a leading China manufacturer, we provide consistent quality, stable supply, competitive wholesale pricing, OEM services, and strict third-party-verified safety standards for global supplement brands.