Bulk Creatine Phosphate Powder Supplier in China

High-Purity Creatine Phosphate raw ingredients for Sports Nutrition, Clinical Research & Advanced Performance Formulations

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What is Creatine Phosphate?

Creatine Phosphate, also known as phosphocreatine, is a high-energy phosphorylated form of creatine that plays a critical role in cellular ATP regeneration, especially in muscle tissue during short bursts of intense activity. Unlike botanical extracts, creatine phosphate is not derived from plants; it is synthesized for commercial use and naturally occurs in meat and fish as part of the body’s phosphagen energy system.

The standard Creatine Phosphate CAS No. 67-07-2 typically corresponds to the molecular formula C4H10N3O5P with a molecular weight of approximately 211.11 g/mol, while Creatine Phosphate Disodium Salt Tetrahydrate (CAS No. 922-32-7, C4H8N3Na2O5P) is a more stable and water-soluble form commonly used in formulations. It is also known by several other names including phosphocreatine, creatine phosphate disodium salt tetrahydrate, N-Methyl-N-(phosphonocarbamimidoyl)glycine, phosphorylcreatine, creatine-P, phosphagen, and fosfocreatine. High-quality bulk material is typically standardized to ≥98% purity, appears as a white crystalline powder, and demonstrates good water solubility, especially in disodium salt form, supporting efficient absorption and high bioavailability in advanced sports nutrition and energy metabolism products. It is commonly supplied in 25kg fiber drums with double PE inner bags for international export. As the leading bulk Creatine Phosphate powder supplier in China, Provita Biotech provides high-purity phosphocreatine raw materials, full COA and documentation support, and OEM services including capsules, tablets, and custom formulations. In addition to creatine phosphate, we also supply other popular creatine derivatives such as Creatine Monohydrate, Creatine HCl, Creatine Ethyl Ester, Micronized Creatine, and Tri-Creatine Malate to support diverse performance nutrition product development.

Bulk Creatine Phosphate Powder Supplier in China

Creatine Phosphate vs Monohydrate

In advanced performance nutrition formulations, Creatine Phosphate (Phosphocreatine) is often positioned as a premium alternative to Creatine Monohydrate due to its direct role in ATP regeneration. While creatine monohydrate must first be converted into phosphocreatine inside muscle cells, creatine phosphate already contains the high-energy phosphate group responsible for rapid ATP recycling. This makes it particularly attractive for high-end, fast-acting, and differentiated sports nutrition products. However, cost, stability, and market familiarity still make creatine monohydrate the dominant mainstream ingredient. Below is a comprehensive technical comparison for B2B buyers and formulation specialists.

ItemCreatine Phosphate (Phosphocreatine)Creatine Monohydrate
CAS Number67-07-26020-87-7
Common Salt FormCreatine Phosphate Disodium Salt Tetrahydrate (CAS 922-32-7)
Other NamesPhosphocreatine, Creatine-P, Phosphagen, Fosfocreatine, N-Methyl-N-(phosphonocarbamimidoyl)glycineCreatine hydrate, Methylguanidinoacetic acid monohydrate
Molecular FormulaC4H10N3O5PC4H9N3O2·H2O
Molecular Weight~211.11 g/mol~149.15 g/mol
AppearanceWhite crystalline powderWhite crystalline powder
Food SourcesNaturally present in meat & fish (as phosphocreatine in muscle tissue)Naturally present in meat & fish (as creatine)
Standard Specification≥98%≥99%
Purity (Commercial)98% typical99%–99.9% typical
Water SolubilityModerate to good (better in disodium salt form)Moderate
BioavailabilityHigh (direct phosphorylated form)High (well-studied absorption)
Potency in ATP RegenerationDirect ATP phosphate donorRequires intracellular phosphorylation
Typical Dosage1–3 g/day (premium formulas)3–5 g/day standard maintenance
Loading PhaseNot typically requiredOften 20 g/day for 5–7 days (optional)
Half-Life (Physiological Turnover)Rapid turnover in muscle cellsConverted to phosphocreatine intracellularly
StabilityLess stable; sensitive to moisture & heatHighly stable under normal storage
Popularity in MarketNiche / premium ingredientExtremely popular / global standard
Clinical Research VolumeLimited compared to monohydrateExtensive research support
Pricing (Bulk Range)High — typically 3–8× monohydrateLow — highly cost-effective
Main BenefitsRapid ATP support, high-end positioning, premium differentiationProven strength gains, muscle mass support, cost-efficient
Regulatory AcceptanceAccepted as creatine derivativeWidely approved and recognized globally
Target MarketPremium sports nutrition, clinical energy formulasMass-market sports supplements
Formulation StrategyUsed in advanced pre-workout blendsStandalone powder, capsules, tablets

Creatine Phosphate Certificate of Analysis(COA)

ProVita Biotech’s Creatine Phosphate Powder Certificate of Analysis (COA) demonstrates high purity and strict quality control in accordance with international standards for dietary supplement raw materials. The tested batch shows an Assay ≥98.0% (Result: 100.66%), with creatine content at 58.21% (Spec: 58.0–60.0%) and phosphate at 42.45% (Spec: 40.0–43.0%), confirming accurate composition and premium-grade potency. Loss on Drying is 0.82% (≤2.0%), and Residue on Ignition is 0.08% (≤0.60%), ensuring low moisture and minimal inorganic residue. Heavy metals are tightly controlled: Total Heavy Metals ≤10 ppm, Arsenic ≤1 ppm, Lead ≤3 ppm, Cadmium ≤1 ppm, and Mercury ≤0.1 ppm, all conforming to specification. Microbiological limits meet stringent safety requirements, including Total Plate Count ≤1000 cfu/g, Yeast & Mold ≤100 cfu/g, E. coli ≤10 cfu/g, Staphylococcus aureus ≤10 cfu/g, and Salmonella Negative/25g. The product passes 100% through 40 mesh, appears as a white crystalline powder, and is packaged in 25kg fiber drums with double-layer polyethylene inner bags, stored under cool, dry conditions. Analytical testing is conducted according to in-house quality standards aligned with ISO 9001 and ISO 22000 systems, with validated analytical methods (HPLC/chemical titration, heavy metal ICP analysis, and microbiological testing) to ensure accuracy and compliance. This batch fully conforms to internal and export standards, meeting international supplement-grade requirements and third-party quality expectations. ProVita Biotech is committed to delivering safe, high-purity bulk Creatine Phosphate powder to supplement manufacturers and global distributors with strict quality assurance and full documentation support.Creatine Phosphate COA

Application

Sports Nutrition & Pre-Workout Formulations

Creatine Phosphate powder is primarily used in high-performance sports nutrition products designed to support rapid ATP regeneration during short, high-intensity exercise. As a direct phosphorylated form of creatine, it plays a key role in explosive power, sprint performance, and strength training formulas. It is commonly formulated into pre-workout powders, performance capsules, and advanced creatine blends, especially in premium sports supplement lines targeting professional athletes and serious fitness users.

Energy Metabolism & Muscle Recovery Supplements

Phosphocreatine supports cellular energy recycling by replenishing ATP levels in muscle cells. This makes bulk Creatine Phosphate powder suitable for energy metabolism products and muscle recovery formulations. It is often combined with ingredients such as beta-alanine, creatine monohydrate, ATP, or B vitamins to create synergistic energy-support supplements aimed at reducing fatigue and enhancing post-exercise recovery.

Clinical & Advanced Performance Research Products

Due to its biochemical role in the phosphagen system, Creatine Phosphate raw material is also used in specialized formulations for research and advanced performance applications. It is positioned as a premium creatine derivative in innovative supplement development, particularly for brands seeking differentiation beyond standard creatine monohydrate. Its higher-end positioning makes it attractive for niche, science-driven sports nutrition and functional health products.

Creatine Phosphate Manufacturing Process

ProVita Biotech’s Creatine Phosphate Powder 98% is manufactured through a strictly controlled chemical phosphorylation process designed to ensure high purity, stability, and compliance with international supplement-grade standards. The process begins with purified water being introduced into a reaction vessel and heated under controlled conditions. Phosphoric acid is then added into the reaction still, followed by continuous stirring to ensure uniform dispersion. High-purity creatine raw material is gradually introduced into the system, and the phosphorylation reaction proceeds under controlled temperature and agitation for approximately 4-5 hours, allowing complete conversion into creatine phosphate. After the reaction is completed, the mixture temperature is carefully lowered to stabilize the product and promote crystallization. The material then undergoes centrifugation to separate solids from the liquid phase, followed by purified water washing to remove residual impurities and unreacted materials. The isolated product is subsequently subjected to controlled drying, ensuring moisture levels meet specification (Loss on Drying ≤2.0%), and then milled to achieve uniform particle size (100% pass 40 mesh). Finally, the finished Creatine Phosphate 98% white crystalline powder is packed in 25kg fiber drums with double-layer polyethylene inner bags under clean and dry conditions.

Throughout production, ProVita Biotech applies strict in-process quality control measures, including assay verification (≥98.0%), heavy metal testing (Pb ≤3 ppm, As ≤1 ppm, Cd ≤1 ppm, Hg ≤0.1 ppm), residue on ignition control (≤0.60%), and microbiological safety standards (TPC ≤1000 cfu/g, Salmonella Negative/25g). Analytical methods such as HPLC, titration analysis, ICP testing, and microbiological examination are conducted to ensure compliance. The final bulk Creatine Phosphate powder meets international supplement raw material standards and passes third-party quality testing, reflecting ProVita Biotech’s commitment to delivering safe, high-purity ingredients to global supplement manufacturers and distributors.

Flow chart of Creatine Phosphate Manufacturing Process

Creatine Phosphate Benefits

  • Supports rapid ATP regeneration by directly donating a phosphate group to ADP for immediate energy production
  • Enhances explosive power and strength during short-duration, high-intensity exercise
  • Improves sprint performance, weightlifting output, and anaerobic capacity
  • Supports muscle endurance in repeated high-intensity training sessions
  • Promotes faster energy recovery between sets and training intervals
  • Contributes to efficient cellular energy metabolism in muscle tissue
  • Provides a premium creatine derivative option for advanced sports nutrition formulations
  • Suitable for capsules, tablets, and powder blends in performance supplement products
  • Used in high-end pre-workout and strength support formulations for differentiated product positioning

Where to buy bulk Creatine Phosphate Powder?

As a leading Creatine Phosphate pure ingredient supplier in China, we provide high quality phosphocreatine raw material for sports nutrition manufacturers, supplement brands, and global distributors.

Our bulk Creatine Phosphate powder is produced under strict GMP and ISO quality systems, with full third-party testing, COA, MSDS, and complete export documents available. We support Kosher and Halal certificates upon request and ensure every batch meets international supplement-grade standards.

ProVita Biotech offers:

  • Factory wholesale supply with competitive bulk pricing
  • High purity Creatine Phosphate 98% white crystalline powder
  • Stable production capacity and fast global shipping
  • OEM services including capsules, tablets, and custom formulations
  • Private label and contract manufacturing support
  • Free sample for qualified supplement manufacturers and distributors

As a professional China supplier and factory, we focus on ingredient purity, safety, and long-term partnership. Whether you need small trial quantities or large-scale wholesale orders, ProVita Biotech delivers consistent quality and reliable supply.

Contact us today to get the latest bulk Creatine Phosphate powder price and technical documents from a trusted China manufacturer.

FAQs

ProVita Biotech supplies high-end nutraceutical-grade and pharmaceutical-grade Creatine Phosphate powder with guaranteed purity of ≥98.0% or ≥99.0% depending on customer requirements. Assay is verified by HPLC and titration methods. Impurities such as creatinine and dicyandiamide are strictly controlled within international safety limits for EU and US markets.

Our production operates under strict quality systems and holds:

  • GMP certification

  • ISO 9001:2015

  • ISO 22000 / FSSC 22000

  • Halal certification

  • Kosher certification

  • Batch-specific COA with every shipment

All documentation is available for supplement manufacturers, importers, and distributors.

Heavy metals including Lead, Arsenic, Mercury, and Cadmium are tested using ICP-MS to ensure compliance with global supplement standards. Microbiological testing includes Total Plate Count, Yeast and Mold, E. coli, Salmonella, and Staphylococcus aureus. Each batch meets strict international food and nutraceutical regulations.

Our Creatine Phosphate is produced via controlled chemical phosphorylation of high-purity creatine, followed by precise crystallization and low-temperature vacuum drying. This prevents degradation into creatinine and ensures molecular stability. The final product is milled and standardized to achieve uniform mesh size and ≥98–99% purity.

Yes. ProVita Biotech provides complete OEM solutions, including:

  • Custom particle sizing from 80 mesh to 200 mesh

  • Custom blend formulations such as Creatine Phosphate with electrolytes

  • Capsule and tablet manufacturing

  • Sachets and retail-ready packaging

  • Private label and contract manufacturing services

We support both bulk raw material supply and finished product development.

Yes. We provide free samples for qualified supplement manufacturers, sports nutrition brands, dietary supplement companies, functional food producers, importers, and distributors to support product evaluation and formulation testing.

Yes. We provide volume-based wholesale pricing:

  • 25 kg – 250 kg: Standard bulk pricing

  • 250 kg – 1,000 kg: Professional tier pricing

  • 1,000 kg or above: Strategic partner contract pricing

Contact us for the latest bulk Creatine Phosphate powder price in China.

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