Bulk Hydroxytyrosol Powder Supplier in China
Pure hydroxytyrosol powder Factory for dietary supplements, cosmetics. Free sample. Potent antioxidant for cardiovascular health, immunity
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What is Hydroxytyrosol?
Hydroxytyrosol is a potent natural polyphenol primarily found in olives and olive leaves, recognized for its strong antioxidant and cardiovascular health benefits. It is also known as 3,4-Dihydroxyphenylethanol (CAS No. 10597-60-1), with the molecular formula C8H10O3 and a molecular weight of 154.16 g/mol. In its pure form, Hydroxytyrosol 99% (produced by fermentation) appears as a white crystalline powder, highly soluble in water, and shows excellent bioavailability. Popular natural specifications include 20% and 25% Hydroxytyrosol extracts, while Provita Biotech can supply both natural and fermented Hydroxytyrosol ingredients to meet diverse formulation needs. Standard packaging is 25kg per drum for powder, and Hydroxytyrosol oil is also available in 1kg, 5kg, and 10kg aluminum bottles. With OEM services for capsules, tablets, and private label solutions, Provita Biotech, the leading bulk Magnesium Lactate powder supplier in China, delivers high-quality Hydroxytyrosol ingredients for global nutraceutical, cosmetic, and pharmaceutical industries.
Hydroxytyrosol vs Oleuropein
Hydroxytyrosol is the smaller, more potent antioxidant per mg, with higher water solubility and faster bioavailability, so it is often preferred when formulators want a strong, fast-acting antioxidant or a standardized active ingredient. Oleuropein is a larger glycoside found in whole olive leaf and fruit that offers broader “whole-extract” benefits and greater chemical stability in some formulations; it can act as a precursor to hydroxytyrosol in vivo. For targeted antioxidant activity, hydroxytyrosol (especially high-purity 99% HPLC) is usually the better choice. For cost-sensitive, full-spectrum olive leaf extracts or formulations relying on synergistic phytochemicals, oleuropein can be the better option.
| Item | Hydroxytyrosol | Oleuropein |
|---|---|---|
| CAS Number | 10597-60-1 | 32619-42-4 |
| Other Names | 3,4-Dihydroxyphenylethanol; HT | Oleuropein (OL); elenolic acid glucoside derivative |
| Molecular Formula | C8H10O3 | C25H32O13 |
| Molecular Weight | 154.16 g·mol⁻¹ | ~540.5 g·mol⁻¹ |
| Appearance | White crystalline powder | Pale yellow to off-white crystalline powder or amorphous extract |
| Food Sources | Olive fruit, olive oil, olive leaves | Olive leaf, unripe olives, olive fruit extract |
| Common Specifications | 20%, 25% (natural extracts); 99% HPLC (fermentation produced) | 10%–40% common in extracts; purified oleuropein up to ~95% available |
| Typical Purity for Commercial Use | 20% / 25% natural extracts; 99% pure for actives | 20% extract common; 40% or higher for standardized extracts; purified grades cost more |
| Solubility | Good water solubility (polar small molecule) | Poorer water solubility – glycoside increases polarity but overall less soluble than HT; better in hydroalcoholic solvents |
| Bioavailability | High and rapid absorption; short plasma peak time | Moderate – oleuropein is metabolized to hydroxytyrosol and other metabolites, so bioavailability depends on metabolism |
| Potency (antioxidant per mg) | High – strong free radical scavenger per mg | Moderate – antioxidant activity present but per mg potency is generally lower than pure hydroxytyrosol |
| Typical Human Dosage (common ranges) | Often formulated 5–50 mg/day depending on product concept (varies by claim and regulation) – product-specific | Often formulated 50–300 mg/day for olive leaf extracts (varies widely by extract standard) |
| Half-life (approx) | Short – plasma levels peak and decline over hours (approx 1–3 hours) | Longer apparent effect because of metabolism to hydroxytyrosol; parent compound half-life variable and depends on formulation |
| Stability | Reasonably stable as powder but sensitive to prolonged exposure to air/light in solution – prone to oxidation if not formulated/stabilized | Generally more stable in extract form; glycoside bond can confer extra stability vs free phenol |
| Popularity / Market Use | High demand in nutraceuticals and cosmetics for antioxidant and cardiometabolic support – premium ingredient | Widely used as olive leaf extract standard in supplements, herbal products, and functional foods |
| Pricing (large range) | Typically higher per kg for high-purity grades (99% HPLC) – premium price for fermented 99% material | Generally lower per kg for common extract grades; purified oleuropein and high-standard extracts raise cost |
| Main Benefits | Potent antioxidant activity; supports cardiovascular health markers and skin protection; used when a standardized active is required | Broad olive-leaf benefits – antioxidant, antimicrobial, metabolic support; offers full-extract synergy and precursor to HT |
| Notes / Formulation Considerations | Ideal for formulations requiring a defined, high-potency active; often used in capsules, tablets, beverages, and topical antioxidants | Better when formulator wants whole-extract marketing or multi-component effects; may require conversion to HT in vivo for some endpoints |
Hydroxytyrosol Certificate of Analysis(COA)
ProVita Biotech Hydroxytyrosol powder batch 20250523 shows 99.08 percent assay by HPLC, 0.44 percent max individual impurity, below 10 ppm total heavy metals (lead 2 ppm, arsenic 2 ppm, cadmium 1 ppm, mercury 0.1 ppm) and below 10 ppm residual solvents verified with USP467 GC-MS. The 100 kg lot is packed in 25 kg double polyethylene bag food grade drums, produced under ISO 9001 and HALA systems, audited by Intertek, and meets USP40, EP10, ISO22000 and EU 231/2012 standards, giving supplement manufacturers and distributors a pure, safe hydroxytyrosol 99 percent bulk ingredient that satisfies international and third party quality requirements.
Application
Dietary Supplements
Hydroxytyrosol is a premium antioxidant ingredient used in capsules, tablets, and functional foods to support heart health, immune defense, and healthy aging.
Cosmetics
Thanks to its strong antioxidant and anti-aging properties, Hydroxytyrosol is widely applied in skincare creams, serums, and hair products to protect against oxidative stress and promote youthful skin.
Pharmaceuticals
Hydroxytyrosol is studied for its cardioprotective, neuroprotective, and anti-inflammatory effects, making it a valuable ingredient in pharmaceutical formulations targeting chronic health conditions.
Hydroxytyrosol Manufacturing Process
1. Frozen Bacterial Strains
The process begins with carefully preserved frozen bacterial strains that have been engineered for efficient hydroxytyrosol biosynthesis. These strains are stored under strict cryogenic conditions to maintain genetic stability and high productivity.
2. Seed Culture
The frozen strains are thawed and introduced into a nutrient-rich medium to form the seed culture. This stage allows the bacteria to recover, multiply, and prepare for large-scale fermentation.
3. Fermentation
The active seed culture is transferred into fermentation tanks under controlled temperature, pH, and oxygen conditions. During fermentation, the bacteria grow rapidly and establish an environment suitable for hydroxytyrosol production.
4. Biosynthesis (with L-Tyrosine Supplementation)
L-Tyrosine, the essential precursor, is fed into the culture. The bacterial metabolic pathway converts L-Tyrosine through enzymatic reactions into hydroxytyrosol. This biosynthetic route ensures high yield, sustainability, and avoids reliance on olive sources.
5. Isolation
Once biosynthesis is complete, the culture broth is subjected to separation processes to isolate hydroxytyrosol from bacterial biomass and fermentation residues. This step concentrates the target compound for further refinement.
6. Filtration
The isolated solution undergoes multiple filtration steps to remove impurities, residual cells, proteins, and other byproducts. Advanced membrane filtration and microfiltration ensure purity and safety.
7. Extraction
Hydroxytyrosol is extracted using eco-friendly solvents or resin adsorption methods, followed by elution. This ensures selective recovery of hydroxytyrosol while minimizing degradation and contamination.
8. Desiccation
The purified hydroxytyrosol solution is dried, typically through spray-drying or vacuum desiccation, to obtain a fine powder. Controlled drying conditions preserve stability, bioactivity, and prevent oxidation.
9. Packaging
The final product, Hydroxytyrosol Powder 99%, is collected and sealed in moisture-proof, light-protective packaging. All packaging is performed in GMP-certified cleanrooms to prevent contamination.
Hydroxytyrosol Benefits
- Powerful Antioxidant: Neutralizes free radicals and protects cells from oxidative stress.
- Supports Heart Health: Promotes healthy blood pressure and circulation.
- Anti-Inflammatory Properties: Helps reduce inflammation and support joint comfort.
- Boosts Immune System: Enhances the body’s natural defenses against infections.
- Neuroprotective Effects: Supports brain health and cognitive function.
- Skin Health Benefits: Protects against UV damage and promotes youthful skin.
- Anti-Aging Support: Helps slow cellular aging and maintain vitality.
- Metabolic Health: Supports healthy cholesterol and blood sugar levels.
Where to buy bulk Hydroxytyrosol?
At ProVita Biotech Co., Ltd., we are the leading Hydroxytyrosol powder supplier in China, specializing in bulk Hydroxytyrosol powder manufacturing directly from our factory. With years of expertise as a trusted wholesale supplier, we provide high-purity Hydroxytyrosol 99% that meets international quality standards.
Our bulk Hydroxytyrosol powder is widely used in Dietary Supplement applications, including OEM capsules and tablets. Every batch is 3rd Party Lab Tested, Safe Heavy Metal Tested, and manufactured in our GMP Certified facility. We also provide full certifications including Kosher, Halal, and ISO to ensure compliance with global markets.
Why Choose ProVita Biotech?
- Direct China factory supplier with competitive Hydroxytyrosol bulk and wholesale pricing
- High-quality ingredients with consistent purity (99%)
- Professional OEM services for custom capsules, tablets, and blends
- Certificates available: GMP, Kosher, Halal, ISO
- Flexible packaging and fast global shipping
- Free sample available for quality evaluation
- Transparent quality assurance with third-party testing
Whether you are searching for bulk Hydroxytyrosol powder, or exploring high quality Hydroxytyrosol oil and other nutraceutical ingredients, ProVita Biotech ensures premium sourcing solutions tailored to your needs.
FAQs
Our bulk Hydroxytyrosol powder is manufactured at 99% purity, confirmed through HPLC analysis and 3rd Party Lab Tested to meet international quality standards.
We use an advanced fermentation and biosynthesis process starting from L-Tyrosine, ensuring consistent yield, sustainable production, and high purity. The process follows GMP Certified standards.
Every batch of Hydroxytyrosol comes with GMP, Kosher, Halal, ISO certificates, along with Safe Heavy Metal Tested reports and complete third-party testing documents for regulatory compliance.
Our standard MOQ is 1kg for trial orders, with bulk and wholesale options available from 25kg/drum packaging for long-term supply.
Yes, ProVita Biotech specializes in OEM Hydroxytyrosol formulations, including capsules, tablets, and blends, tailored to your private label requirements.
Yes, we provide free Hydroxytyrosol powder samples for quality evaluation before bulk purchasing. Shipping costs are usually covered by the client.
As a direct China factory supplier, we offer highly competitive bulk Hydroxytyrosol prices without middlemen. We also supply other nutraceuticals such as Magnesium Lactate at factory-direct rates.
For in-stock Hydroxytyrosol, we ship within 3-5 working days. For larger OEM or custom orders, production lead time is 2-4 weeks depending on specifications.
Yes, we offer flexible packaging options according to customer needs, including small packs for retail and standard bulk drums for wholesale buyers.