Bulk CREAONE™ Instant Creatine Monohydrate Powder Supplier in China

100% water-soluble, fast-dissolving creatine monohydrate engineered for smooth mixing in sports nutrition powders and beverage formulations. Factory-direct bulk supply from Provita Biotech.

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Bulk CREAONE Instant Creatine Monohydrate Powder Supplier in China

CREAONE™ Instant Creatine Monohydrate Powder

Product NameCREAONE™ Instant Creatine Monohydrate Powder
Other NamesInstant Creatine Powder, Fast-Dissolving Creatine Monohydrate, Quick-Mixing Creatine Powder, Instantized Creatine
CAS Number6020-87-7
Molecular FormulaC₄H₉N₃O₂·H₂O, also written as C₄H₁₁N₃O₃
Molecular Weight149.15 g/mol
Branded IngredientCREAONE™
Main Specifications99.99% Pure, Instant Soluable, Dicyandiamide Not detected, Dihydrotriazine Not detected
Appearance/colorWhite powder
Bulk PackageDouble PE bags in a net 25 kg cardboard box, custom package
Annual Capability 2000 tons

What Is CREAONE™ Instant Creatine Monohydrate Powder?

CREAONE™ Instant Creatine Monohydrate Powder is ProVita Biotech’s branded fast-dissolving creatine ingredient for sports nutrition brands, supplement manufacturers, contract manufacturers and ingredient distributors. It combines rapid dissolution performance with ≥99.99% purity and strict control of creatine-related manufacturing byproducts.

The ingredient remains creatine monohydrate, with CAS No. 6020-87-7, molecular formula C₄H₉N₃O₂·H₂O and molecular weight 149.15 g/mol. These identity details are consistent with the PubChem creatine monohydrate record.

“Instant” describes the powder’s improved wetting, dispersion and dissolution characteristics. It does not mean that CREAONE is a different creatine salt or a new active molecule. The ingredient retains the established identity of creatine monohydrate while offering a cleaner mixing experience for water-based powders and sports nutrition formulations.

According to the available product performance data, CREAONE fully dissolves within 30 seconds at a concentration of 1.2 g per 100 mL. This rapid dissolution helps reduce floating powder, clumping, visible sediment and the gritty mixing experience commonly associated with conventional creatine powders.

ProVita Biotech also supplies High Purity Creatine Monohydrate Powder 99.99%, Micronized Creatine Monohydrate 500 Mesh Powder and Creatine Monohydrate 200 Mesh Powder for buyers requiring different purity, particle-size and formulation characteristics.

Why Choose CREAONE™ Instant Creatine?

Rapid 30-Second Dissolution

CREAONE is engineered for rapid dissolution in water. Under the stated test condition of 1.2 g per 100 mL, the powder fully dissolves within 30 seconds. This supports cleaner mixing and more convenient consumer use in powder-based supplements.

≥99.99% Purity

CREAONE has a chromatographic purity specification of ≥99.99%, together with a dry-basis assay specification of ≥99.5%. The supplied COA for batch NJCM25121501 recorded a dry-basis assay result of 100.0%.

Ultra-Low Creatinine

The creatinine specification is ≤30 mg/kg. The referenced production batch contained only 7 mg/kg, equivalent to 7 ppm, demonstrating strict control of creatine degradation and manufacturing conditions.

DCD and DHT Not Detected

Dicyandiamide and dihydrotriazine are unwanted byproducts that may be associated with creatine production. Neither compound was detected in the referenced CREAONE batch.

Clean Heavy-Metal and Microbiological Profile

CREAONE is tested for lead, arsenic, cadmium, mercury, total heavy metals and microbiological parameters. The referenced batch recorded less than 10 CFU/g for both total plate count and yeast and mold, with E. coli, Salmonella and Staphylococcus aureus negative.

Cost-Effective Premium Positioning

CREAONE provides rapid dissolution and premium impurity control without requiring brands to move away from creatine monohydrate. It offers a cost-effective option for brands seeking a differentiated instant creatine product with transparent technical documentation.

CREAONE™ Dissolution and Mixing Performance

Creatine monohydrate has moderate equilibrium solubility in room-temperature water. CREAONE is designed to improve how rapidly the powder wets, disperses and dissolves under appropriate concentration and mixing conditions.

At a concentration of 1.2 g per 100 mL, CREAONE fully dissolves within 30 seconds according to the supplied performance data. For accurate B2B evaluation, dissolution testing should specify water temperature, sample concentration, agitation method, mixing time and endpoint.

Water volume, temperature, pH, other formula ingredients and the amount of creatine per serving can all affect the appearance of the finished beverage. A five-gram serving added to a small amount of cold water may behave differently from the stated 1.2 g/100 mL test condition.

For powder supplements and drink mixes, CREAONE offers several formulation advantages:

  • Faster wetting and dispersion
  • Reduced clumping during mixing
  • Less visible sediment under suitable conditions
  • Smoother consumer mixing experience
  • Better compatibility with flavored powder blends
  • Easier incorporation into sachets and stick packs

Rapid dissolution should not be described as proof of superior absorption or greater biological efficacy. Scientific reviews continue to identify creatine monohydrate as the reference form, with no convincing evidence that alternative creatine forms provide superior bioavailability, efficacy or safety. See the published review of creatine bioavailability and alternative forms.

CREAONE™ Instant Creatine vs Micronized and Regular Creatine

Comparison CREAONE™ Instant Creatine Micronized Creatine 500 Mesh Regular Creatine 200 Mesh
Chemical Identity Creatine monohydrate Creatine monohydrate Creatine monohydrate
Primary Advantage Rapid dissolution and easier mixing Fine particle size and improved dispersion Standard economical creatine grade
Dissolution Performance Fully dissolved within 30 seconds at 1.2 g/100 mL Fine particles disperse quickly, but dissolution depends on concentration and conditions Usually requires more mixing and may leave more visible sediment
Particle Positioning Instant-dissolving grade Ultra-fine 500 mesh grade Conventional 200 mesh grade
Purity ≥99.99% Batch-specific specification Batch-specific specification
Creatinine ≤30 mg/kg, tested at 7 mg/kg Batch-specific specification Batch-specific specification
Best Applications Premium instant powders, sachets and powdered sports drinks Gummies, powders, capsules and fine-texture blends Standard powders, capsules and tablets
Main Buyer Priority Mixing experience plus purity Particle size and mouthfeel Cost and general-purpose use
Instant, micronized and regular creatine monohydrate share the same active chemical identity. CREAONE’s principal advantage is faster dissolution and improved formulation performance, not a different physiological mechanism.

CREAONE™ Certificate of Analysis

The Certificate of Analysis for CREAONE™ Instant Creatine Monohydrate Powder confirms high purity, low levels of synthesis byproducts, controlled heavy metals and strong microbiological quality. The referenced batch, NJCM25121501, was manufactured on December 15, 2025, with a retest date of December 14, 2028.

The COA differentiates between assay and purity. Dry-basis assay measures the amount of creatine monohydrate and has a specification of ≥99.5%, with a batch result of 100.0%. The separate chromatographic purity specification is ≥99.99%, tested according to USP <621>.

Creatinine was measured at only 7 mg/kg, below the limit of ≤30 mg/kg. Dicyandiamide, dihydrotriazine, sulfate, cyanide and residue on ignition were not detected.

Test ItemSpecificationCOA ResultTest Method
AppearanceWhite powderConformsOrganoleptic
IdentificationCorresponds to reference standardConformsUSP <621>
Assay, Dry Basis≥99.5%100.0%USP <621>
Purity≥99.99%ConformsUSP <621>
Sulfate≤0.03%Not detectedUSP <221>
Loss on Drying≤12.0%11.8%USP <731>
Residue on Ignition≤0.1%Not detectedUSP <281>
Creatinine≤30 mg/kg7 mg/kgUSP <621>
DicyandiamideNot detectedNot detectedUSP <621>
DihydrotriazineNot detectedNot detectedUSP <621>
CyanideNot detectedNot detectedUSP <851>
Total Heavy Metals≤10 ppm<10 ppmChP 2020 Part 4 0821
Lead≤1.0 ppm<1.0 ppmUSP <233>
Arsenic≤1.0 ppm<1.0 ppmUSP <233>
Cadmium≤1.0 ppm<1.0 ppmUSP <233>
Mercury≤0.1 ppm<0.1 ppmUSP <233>
Total Plate Count≤1,000 CFU/g<10 CFU/gISO 4833-1
Yeast and Mold≤100 CFU/g<10 CFU/gISO 21527
E. coliNegative in 25 gNegativeISO 16649-3
SalmonellaNegative in 25 gNegativeISO 6579-1
Staphylococcus aureusNegative in 25 gNegativeUSP <62>

CREAONE is packed in double PE bags inside a net 25 kg cardboard box. Each commercial shipment can be supported with batch documentation such as the COA, product specification, TDS and other quality documents according to customer requirements. Third-party testing can be arranged when required by an importer, distributor or finished-product manufacturer.  Download the Instant Creatine Monohydrate Powder COA here.

CREAONE™ Instant Creatine Applications

CREAONE™ Instant Creatine Monohydrate Powder can be used in standalone creatine powders, pre-workout and post-workout formulas, protein shakes, mass gainers, electrolyte powders, powdered sports drinks, sachets, stick packs, capsules, tablets, effervescent products, cognitive health supplements and healthy-aging formulations. Its rapid dissolution is especially valuable in products where consumers mix the finished powder directly with water.

Standalone Instant Creatine Powders

CREAONE can be packed as an unflavored single-ingredient creatine powder or blended with natural flavors, sweeteners and acidulants. The instant grade helps reduce clumping and visible residue, supporting a cleaner consumer experience in tubs, pouches, sachets and stick packs.

ProVita Biotech provides OEM creatine powder supplement manufacturing for brands requiring custom serving sizes, flavors, bottles, pouches, labels and retail packaging.

Pre-Workout and Post-Workout Formulas

Instant creatine monohydrate can be combined with beta-alanine, amino acids, electrolytes, carbohydrates, caffeine and other sports nutrition ingredients. Faster dissolution helps the creatine disperse more evenly throughout multi-ingredient powder blends.

Protein Shakes and Mass Gainers

CREAONE can be incorporated into whey protein, plant protein, meal replacement and mass-gainer powders. It supports more uniform distribution of creatine in the finished blend while reducing the possibility of coarse creatine sediment after mixing.

Powdered Sports Drinks and Electrolyte Formulas

Rapid dissolution makes CREAONE suitable for powdered sports drinks, electrolyte sachets and water-mixable fitness products. Formulators should evaluate flavor, pH, concentration, water temperature and serving volume during development.

Capsules, Tablets and Effervescent Products

CREAONE can be used in capsules and tablets when brands want to combine premium purity with rapid disintegration after consumption. It can also be evaluated for effervescent formats, subject to moisture protection and finished-product stability testing.

Cognitive Health and Healthy-Aging Formulations

Creatine participates in cellular energy metabolism in both muscle and brain tissue. CREAONE can therefore be considered for nootropic, mental-energy, active-aging and healthy-longevity formulations. Claims should remain consistent with the regulations and available evidence in the destination market.

Gummies and Ready-to-Drink Products

Creatine gummies and shelf-stable ready-to-drink beverages require additional formulation work because heat, moisture, acidity and storage time can affect creatine stability. ProVita provides separate custom creatine gummy manufacturing for brands developing finished gummy products.

Instant dissolution alone does not establish long-term stability in a liquid beverage. RTD manufacturers should complete product-specific stability testing under the intended pH, processing, temperature and shelf-life conditions. Published research confirms that water activity and temperature influence creatine degradation to creatinine in hydrated systems. See the creatine stability study.

CREAONE™ Instant Creatine Manufacturing and Quality Control

Commercial creatine monohydrate is produced through the controlled reaction of sodium sarcosinate and cyanamide in purified water. The resulting creatine is purified, crystallized, separated and dried before undergoing finishing and quality-control procedures.

The general CREAONE manufacturing and release workflow includes:

Raw Material Qualification → Controlled Synthesis → Filtration and Purification → Crystallization → Centrifugal Separation → Drying → Dissolution-Optimized Finishing → Sieving → Quality Testing → Metal Detection → Packaging

Strict reaction control, purification and crystallization help minimize the formation of creatinine, DCD and DHT. The finished material then undergoes controlled processing intended to improve wetting and dissolution while preserving the chemical identity of creatine monohydrate.

Each production batch is tested for identity, assay, chromatographic purity, creatinine, DCD, DHT, sulfate, cyanide, loss on drying, residue on ignition, heavy metals and microbiological quality before release.

CREAONE is not described in the approved COA or TDS as an alkaline-buffered creatine, creatine salt or hydrogel formula. Brands should therefore identify it as instant creatine monohydrate rather than using unsupported processing terms.

CREAONE™ Instant Creatine Benefits

CREAONE provides two different categories of benefits: formulation benefits specific to the instant grade and the established nutritional functions of creatine monohydrate.

Formulation Benefits

  • Rapid dissolution under the stated test condition
  • Easier wetting and mixing
  • Reduced clumping and visible sediment
  • Better compatibility with powder beverage systems
  • Cleaner consumer mixing experience
  • ≥99.99% purity with strict impurity control
  • Consistent batch documentation and traceability

Strength and Power Support

Creatine helps replenish phosphocreatine stores used to regenerate ATP during repeated high-intensity activity. Consistent supplementation can support strength, explosive power and high-intensity exercise performance.

ATP Energy Regeneration

The phosphocreatine system helps supply rapidly available energy during short, intense activities such as sprinting, resistance training and repeated high-power exercise.

Lean Muscle and Training Support

When combined with resistance training, creatine supplementation can support gains in strength and lean tissue. Creatine should not be presented as a substitute for training, adequate protein intake or an appropriate diet.

Exercise Recovery

Creatine is frequently included in post-workout and recovery formulations. Research has evaluated its potential role in supporting training adaptation, recovery and repeated exercise performance.

Brain Energy and Cognitive Formulations

The brain also uses creatine and phosphocreatine as part of cellular energy metabolism. Research is expanding into cognition, memory and mental-fatigue applications, although brands should avoid overstating product-specific effects.

Creatine monohydrate remains the most extensively studied and evidence-supported creatine form. The International Society of Sports Nutrition position stand reviews its applications in exercise, sport and health.

Recommended Usage

The CREAONE TDS recommends 5 g per serving, once daily, with or without food. Finished-product serving size should be determined according to the target market, consumer group, formula, regulatory requirements and label instructions.

A daily intake of approximately 3-5 g is commonly used in published creatine monohydrate research. A loading phase is not required for regular supplementation, although some research protocols use divided loading doses before moving to a lower daily maintenance intake.

Brands should review finished-product directions and claims with a qualified regulatory professional for each destination market.

Packaging, Transportation and Storage

CREAONE™ Instant Creatine Monohydrate Powder is packed in double food-grade PE bags inside a net 25 kg cardboard box. The double inner liners help protect the powder from moisture and external contamination during storage and international transportation.

Transport the product as a non-hazardous chemical. Keep the packaging sealed and protected from moisture, excessive heat and direct sunlight.

Store in a cool, dry and well-ventilated warehouse. Under the recommended storage conditions and in unopened original packaging, the stated shelf life is 36 months.

Where to Buy Bulk CREAONE™ Instant Creatine Monohydrate Powder

ProVita Biotech Co., Ltd. is a leading bulk instant creatine monohydrate powder manufacturer and supplier in China. We supply CREAONE™ to sports nutrition brands, dietary supplement manufacturers, contract manufacturers, importers and ingredient distributors worldwide.

ProVita exports approximately 1,000 tons of creatine ingredients annually, supporting scalable supply for emerging brands, established sports nutrition companies and global distributors. Buyers can request product samples, batch COAs, specifications, TDS documents and third-party laboratory testing before placing a commercial order.

Why source CREAONE™ from ProVita Biotech?

  • Branded instant creatine monohydrate ingredient
  • Fully dissolved within 30 seconds at 1.2 g/100 mL
  • ≥99.99% purity specification
  • Creatinine ≤30 mg/kg, with a tested result of 7 mg/kg
  • DCD and DHT not detected
  • 25 kg factory bulk packaging
  • Competitive wholesale pricing
  • Free samples for qualified B2B buyers
  • COA, TDS, specifications and technical documentation
  • Third-party testing available
  • Stable large-volume creatine supply
  • Global shipping and export support

ProVita also provides OEM and private-label services for creatine powder supplements, flavored creatine blends, sachets, stick packs, capsules, tablets and gummies. Custom formula, dosage, flavor, packaging and label requirements can be discussed according to the customer’s target market.

Explore ProVita Biotech’s full selection of creatine ingredients or contact us for the latest CREAONE™ instant creatine price per kilogram, minimum order quantity, free sample, COA and wholesale quotation.

FAQs

Instant creatine monohydrate powder is creatine monohydrate processed to improve wetting, dispersion and dissolution in water. It retains the same creatine monohydrate chemical identity while providing a more convenient mixing experience.

Yes. “Instantized creatine” normally describes a creatine monohydrate grade with improved mixing or dissolution properties. It is not automatically a different creatine compound or salt.

CREAONE remains creatine monohydrate. Its main difference is the rapid dissolution performance and ultra-clean impurity profile.

Instant creatine can be better for formulations where fast mixing, lower sediment and consumer convenience are priorities. Regular and instant creatine monohydrate share the same active chemical identity.

The instant grade should not be described as physiologically superior unless product-specific comparative studies demonstrate a difference.

Micronized creatine is milled into smaller particles to improve dispersion and mouthfeel. Instant creatine is designed around rapid wetting and dissolution performance.

A fine micronized powder may disperse quickly but remain suspended rather than fully dissolved. CREAONE was developed to fully dissolve within 30 seconds at 1.2 g/100 mL under the stated test condition.

CREAONE fully dissolves under the stated performance condition of 1.2 g in 100 mL of water within 30 seconds. Actual results in a finished product depend on creatine concentration, water temperature, pH, agitation and other formula ingredients.

For accurate marketing, “100% water soluble” should be accompanied by the tested concentration and conditions rather than presented as unlimited solubility at any dosage.

Not necessarily. Faster dissolution improves mixing and consumer experience, but it does not automatically establish greater intestinal absorption, muscle uptake or biological efficacy.

Creatine monohydrate is already considered highly bioavailable. CREAONE’s primary differentiators are rapid dissolution, purity and impurity control.

CREAONE has a chromatographic purity specification of ≥99.99% and a dry-basis assay specification of ≥99.5%. The referenced batch recorded a 100.0% dry-basis assay and conformed to the ≥99.99% purity requirement.

Creatinine, dicyandiamide and dihydrotriazine are quality indicators associated with creatine production, degradation or insufficient process control. They do not provide the intended nutritional function of creatine.

CREAONE has a creatinine specification of ≤30 mg/kg, with a referenced batch result of 7 mg/kg. DCD and DHT were not detected.

CREAONE’s rapid dissolution can reduce undissolved powder, gritty sediment and poor mixing. However, it should not be marketed as eliminating bloating, gastrointestinal discomfort or water retention without product-specific clinical evidence.

Individual digestive tolerance can also be influenced by dose, serving size, fluid intake and other formula ingredients. Creatine-related intracellular hydration should not be confused with undissolved powder in the digestive tract.

The CREAONE TDS recommends 5 g per serving, once daily. Published creatine monohydrate research commonly uses daily maintenance amounts of approximately 3-5 g.

Finished-product serving directions should be adjusted according to formula design, local regulations and the intended consumer population.

CREAONE can dissolve rapidly in water, but rapid dissolution and long-term beverage stability are different characteristics. Creatine can gradually convert to creatinine in certain hydrated, acidic or high-temperature conditions.

RTD manufacturers should conduct product-specific pH, processing and shelf-life testing before commercialization. Powdered beverages mixed shortly before consumption are generally more straightforward applications.

CREAONE can be evaluated for gummy formulations, but heat, moisture, acidity, dosage loading and shelf stability must be considered. ProVita offers dedicated creatine gummy development and manufacturing for brands requiring finished gummy products.

The standard bulk package is a net 25 kg cardboard box with double PE inner bags. Custom bulk or finished-product packaging can be discussed for qualified commercial and OEM projects.

Yes.

Commercial CREAONE batches can be supplied with a batch-specific COA covering identity, assay, purity, creatinine, DCD, DHT, loss on drying, residue on ignition, heavy metals and microbiological quality.

TDS, specifications, SDS/MSDS, allergen information, non-GMO statements and third-party testing can also be discussed according to customer requirements.

Yes. ProVita Biotech provides OEM and private-label support for instant creatine powders, flavored powder blends, sachets, stick packs, capsules, tablets, effervescent products and selected gummy formats.

Formula, dosage, flavor, sweetener system, packaging, label design, testing and order quantity can be customized according to the project.

Yes. Free CREAONE™ samples are available for qualified supplement manufacturers, sports nutrition brands, contract manufacturers, formulators, importers and ingredient distributors.

Provide your company information, intended application, destination market and estimated annual demand when requesting a sample.

The wholesale price depends on order quantity, contract volume, packaging, testing requirements, destination, freight cost and OEM services. Contact ProVita Biotech for the current factory price, minimum order quantity and shipping quotation.

Request a wholesale Pricing

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