L-Arginine Alpha Ketoglutarate Powder
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What is L-Arginine Alpha Ketoglutarate?
L-Arginine Alpha-Ketoglutarate (AAKG) is a compound formed by combining the amino acid L-arginine and alpha-ketoglutarate, a key intermediate in the Krebs cycle. Its CAS number is 2322-25-6, and it is also known by other names such as Arginine AKG or AAKG. The molecular formula for L-Arginine Alpha-Ketoglutarate is C6H14N4O3, and it has a molecular weight of 174.2 g/mol. While it does not have a direct botanical source, it is commonly synthesized for use in supplements. AAKG is often found in a white to off-white crystalline powder form. It is used for enhancing nitric oxide production in the body, which may promote better blood flow and muscle performance. The bioavailability of L-Arginine Alpha-Ketoglutarate is high, allowing for improved absorption and utilization in the body. Provita Biotech is the leading bulk L-Arginine Alpha-Ketoglutarate powder supplier in China, providing top-quality ingredients for the dietary supplement industry.
AAKG vs Arginine
L-Arginine and L-Arginine Alpha-Ketoglutarate (AAKG) are both compounds utilized in dietary supplements, particularly for their roles in nitric oxide production and cardiovascular health. Below is a comparative overview of their key characteristics:
| Attribute | L-Arginine | L-Arginine Alpha-Ketoglutarate (AAKG) |
|---|---|---|
| CAS Number | 74-79-3 | 16856-18-1 |
| Other Names | L-2-Amino-5-guanidinopentanoic acid, 2-Amino-5-guanidinopentanoic acid | Arginine AKG, Arginine alpha-ketoglutarate |
| Molecular Formula | C₆H₁₄N₄O₂ | C₆H₁₄N₄O₂·C₅H₆O₅ |
| Molecular Weight | 174.2 g/mol | 320.3 g/mol |
| Appearance | White crystalline powder | White to off-white crystalline powder |
| Purity | Typically ≥98% | Typically ≥98% |
| Bioavailability | High; absorbed through the gastrointestinal tract | High; enhanced absorption due to the presence of alpha-ketoglutarate |
| Potency | Effective in increasing nitric oxide levels and improving blood flow | Enhanced potency due to the synergistic effect of arginine and alpha-ketoglutarate |
| Half-Life | Approximately 1 hour | Approximately 1 hour |
| Stability | Stable under normal storage conditions | Stable under normal storage conditions; may be more stable in certain formulations due to the salt form |
| Popularity | Widely used in supplements for cardiovascular health and athletic performance | Popular in sports nutrition for its potential to enhance exercise performance and recovery |
| Pricing | Generally lower cost per gram compared to AAKG | Generally higher cost per gram due to the additional alpha-ketoglutarate component |
Summary:
Both L-Arginine and AAKG are effective in promoting nitric oxide production and supporting cardiovascular health. However, AAKG offers enhanced potency and bioavailability due to the synergistic effect of arginine and alpha-ketoglutarate. This combination may lead to improved exercise performance and recovery. While AAKG is generally more expensive than L-Arginine, its added benefits may justify the higher cost for individuals seeking enhanced performance outcomes.
Provita Biotech is the leading bulk L-Arginine Alpha-Ketoglutarate powder supplier in China, providing top-quality ingredients for the dietary supplement industry.
L-Arginine Alpha Ketoglutarate COA
The Certificate of Analysis for ProVita Biotech’s L-Arginine Alpha-Ketoglutarate (AAKG) powder demonstrates exceptional quality. The assay (purity) of the AAKG powder is 100.16%, well within the specified range of 98-102%. Heavy metals such as lead, cadmium, mercury, and arsenic are all present in trace amounts of less than 1 ppm, ensuring the product is free from harmful contaminants. Additionally, the residual solvents, including chloride and loss on drying, are well within acceptable limits, with chloride at 0.03% and loss on drying at 0.32%. This confirms that the product meets the highest standards of purity and safety.
Application
Sports Performance & Muscle Growth
L-Arginine Alpha-Ketoglutarate (AAKG) is commonly used in sports nutrition to enhance nitric oxide production, promoting better blood circulation and oxygen delivery to muscles. This results in improved exercise performance, faster muscle recovery, and increased muscle growth.
Cardiovascular Health
AAKG supports healthy blood flow by boosting nitric oxide levels, which helps relax blood vessels and improve circulation. This makes it beneficial for cardiovascular health by potentially lowering blood pressure and enhancing overall heart function.
Weight Loss & Fat Metabolism
AAKG is used in weight management supplements for its potential to enhance fat metabolism. It helps in boosting energy levels during exercise, which may contribute to more effective fat burning and weight loss when combined with a healthy lifestyle.
AAKG Powder Manufacturing Process
ProVita Biotech’s manufacturing process for L-Arginine Alpha-Ketoglutarate (AAKG) powder follows a meticulous and multi-step procedure to ensure a 99% pure product that meets international standards and passes third-party quality tests.
- Condensation: The process begins with the reaction of L-Arginine and Alpha-Ketoglutarate (AKG), utilizing methyl acrylate and methyl dichloroacetate to initiate condensation.
- Neutralization & Washing: The reaction mixture is neutralized with 5% HCl and washed to remove impurities. This step ensures the purity of the product and prepares it for further processing.
- Vacuum Distillation: The liquid undergoes vacuum distillation, separating it from undesirable components, which are discarded as waste.
- Hydrolysis: The esterified product is hydrolyzed with a sodium hydroxide solution and treated with calcium carbonate and sodium bicarbonate to refine the mixture, ensuring optimal purity.
- Filtration & Ion Exchange: Filtration is carried out to remove any remaining solid particles, followed by an ion exchange process to further purify the solution.
- Crystallization: The purified solution undergoes crystallization, and the product is filtered, dried, and micronized to achieve the final powder form.
- Final Purification: The powder undergoes a final decolorization process using activated carbon, ensuring that it meets the highest quality standards.
The resulting AAKG powder is 99% pure, passes rigorous third-party quality tests, and complies with all international standards. It is suitable for use in sports nutrition, cardiovascular health, and various dietary supplements.
L-Arginine Alpha Ketoglutarate Benefits
- Boosts Nitric Oxide Production: Enhances blood flow and improves circulation, promoting better muscle pumps during workouts.
- Improves Exercise Performance: Increases endurance and stamina, helping athletes perform at higher intensity levels.
- Promotes Muscle Growth: Supports protein synthesis and muscle recovery, aiding in muscle development after strenuous exercise.
- Enhances Cardiovascular Health: Helps lower blood pressure and supports healthy heart function by improving vascular health.
- Speeds Up Recovery: Reduces muscle fatigue and soreness, allowing for quicker recovery after physical activity.
- Supports Fat Metabolism: May aid in fat burning by boosting energy levels during exercise, contributing to weight management.
- Improves Amino Acid Balance: Balances amino acids in the body, optimizing metabolic processes and overall health.
- Increases Bioavailability: The combination of L-Arginine and Alpha-Ketoglutarate enhances absorption, ensuring more effective results.
Where to buy AAKG bulk powder?
Looking for premium L-Arginine Alpha Ketoglutarate bulk powder? ProVita Biotech stands as China’s leading AAKG powder manufacturer, delivering pharmaceutical grade AAKG to sports nutrition brands worldwide.
As a GMP certified supplement supplier, we provide:
– Consistently high purity percentage AAKG (99%+)
– Comprehensive COA documentation with every order
– Third-party tested ingredients ensuring quality
– Custom particle size distribution to match your formulation needs
– Competitive pricing for pre-workout ingredient suppliers
Our L-Arginine AKG wholesale service supports nutraceutical companies and fitness supplement brands with this powerful nitric oxide precursor. Each batch undergoes rigorous microbial testing standards and heavy metal testing to ensure your muscle pump enhancer meets international regulations.
ProVita Biotech has established itself as the trusted supplement manufacturing partner for companies seeking exercise performance ingredients at scale. Contact our team today to request samples of our vasodilation supplement raw materials and experience the ProVita difference in bulk amino acid powders.
FAQs
Our pharmaceutical grade AAKG consistently tests at 99%+ purity. Each batch receives comprehensive third-party testing with full documentation provided to our clients.
ProVita Biotech is a GMP certified supplement supplier with ISO 9001 certification. We also provide complete COA documentation with every shipment of our nitric oxide precursor ingredients.
Our standardized manufacturing process includes rigorous quality control checkpoints and microbial testing standards at each production phase, ensuring your vasodilation supplement ingredients maintain consistent efficacy.
Our standard MOQ for L-Arginine AKG wholesale is 25kg, though we offer flexibility for long-term supplement manufacturing partners.
Yes, we manage global logistics for our exercise performance ingredients with established shipping routes to North America, Europe, Australia, and beyond. All international shipments include proper documentation for smooth customs clearance.
We offer customizable particle size distribution tailored to your specific formulation requirements, ensuring optimal mixability in your sports nutrition formulations.
AAKG demonstrates superior bioavailability compared to standard L-Arginine, allowing for enhanced nitric oxide production with smaller dosages in your fitness supplement brands' products.
Our AAKG maintains optimal shelf stability data when stored in a cool, dry environment away from direct sunlight. Properly stored, it maintains potency for up to 24 months.
Yes, as a complete supplement manufacturing partner, we provide custom formulation, blending, and packaging solutions for nutraceutical companies developing AAKG-containing products.
Absolutely. We offer sample quantities of our bodybuilding supplement ingredients for evaluation before committing to larger orders. Standard sample fees are credited toward your first full purchase.
Our tiered pricing structure rewards loyalty with progressive discounts starting at 100kg orders, with additional advantages for quarterly and annual contracts with pre-workout ingredient suppliers.