L-Carnitine Base Powder
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What is L-Carnitine Base?
L-Carnitine Base (CAS No. 541-15-1) is a naturally occurring amino acid derivative that plays a crucial role in energy metabolism by transporting long-chain fatty acids into mitochondria for oxidation. Also known as Levocarnitine, (R)-Carnitine, or 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide inner salt, it has the molecular formula C₇H₁₅NO₃ with a molecular weight of 161.2 g/mol. L-Carnitine is found naturally in animal products like meat, fish, and dairy, but can also be synthesized for supplement purposes. The pure form appears as a white to off-white crystalline powder with a slight characteristic odor, and typically has a bioavailability of 15-25% when taken orally, with absorption rates varying based on formulation and dosing. Provita Biotech stands as the leading bulk L-Carnitine Base Powder supplier in China, offering high-purity material (≥98%) that meets international quality standards for nutritional supplements, functional foods, and pharmaceutical applications.
Acetyl L-Carnitine VS L-Carnitine
Both Acetyl L-Carnitine (ALCAR) and L-Carnitine are beneficial supplements, but they serve slightly different purposes. ALCAR generally offers superior bioavailability, better blood-brain barrier penetration, and more pronounced cognitive benefits, making it preferable for neurological applications and cognitive enhancement. However, it comes with a higher price point. Standard L-Carnitine is more suitable for general energy metabolism, athletic performance, and cardiovascular support at a more affordable cost. The choice between them depends on specific health goals: choose ALCAR for brain health and cognitive function, and L-Carnitine for energy production and cardiovascular benefits. Check L-carnitine L-tartrate bulk Powder here.
| Feature | Acetyl L-Carnitine | L-Carnitine |
|---|---|---|
| CAS Number | 5080-50-2 | 541-15-1 |
| Other Names | ALCAR, ALC, Acetylcarnitine | Levocarnitine, (R)-Carnitine, L-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide inner salt |
| Molecular Formula | C₉H₁₇NO₄ | C₇H₁₅NO₃ |
| Molecular Weight | 203.24 g/mol | 161.2 g/mol |
| Appearance | White to off-white crystalline powder | White to off-white crystalline powder |
| Purity | ≥98% (pharmaceutical grade) | ≥98% (pharmaceutical grade) |
| Bioavailability | Higher (40-60%) due to better absorption | Lower (15-25%) with standard oral formulations |
| Blood-Brain Barrier Penetration | Effectively crosses the blood-brain barrier | Limited ability to cross the blood-brain barrier |
| Potency | More potent for cognitive effects | More focused on energy metabolism effects |
| Half-life | 4-6 hours | 4-12 hours |
| Stability | Generally stable but more sensitive to degradation | More stable in various conditions |
| Popularity | Popular in nootropic and anti-aging communities | More widely used for athletic performance and metabolism |
| Pricing | 25-40% more expensive | More affordable, standard pricing |
| Main Benefits | • Cognitive enhancement • Neuroprotection • Anti-aging effects • Mental fatigue reduction • Memory enhancement • Mood improvement | • Energy production • Fat metabolism • Exercise performance • Heart health • Weight management • Recovery support |
| Target Applications | • Alzheimer’s and dementia • Cognitive decline • Depression and mental fatigue • Neuropathic pain | • Athletic performance • Cardiovascular support • Weight management • Metabolic disorders |
| Side Effects Profile | Generally mild; may cause insomnia if taken late in day | Generally mild; occasionally causes nausea or digestive discomfort |
| Best Time to Take | Morning or early afternoon due to potential stimulating effects | More flexible timing, often before exercise |
| Typical Dosage Range | 500-2000 mg daily | 500-2000 mg daily |
L-Carnitine Base COA
ProVita Biotech’s L-Carnitine Base (batch LCB240411033) demonstrates exceptional quality with an assay purity of 99.6% (within the 98.0-102.0% specification). Safety testing confirms compliance with USP 40 standards, showing minimal heavy metal content with levels well below thresholds: heavy metals <10ppm, arsenic <1ppm, lead <3ppm, cadmium <1ppm, and mercury <0.1ppm. Residual solvents conform to specifications (≤0.5%), while water content measures just 0.11% (below the ≤4.0% limit). The white crystalline powder presents ideal characteristics with pH 7.0 and specific rotation of -30.9°. Additionally, the product shows no detectable cyanide, E.Coli, or Salmonella, with minimal microbiological contamination (TPC and Yeast & Mold <10CFU/g), confirming this pharmaceutical-grade L-Carnitine Base meets all quality and safety requirements.
Application
Athletic Performance Enhancement
L-Carnitine Base serves as a powerful ergogenic aid for athletes and fitness enthusiasts. By facilitating fatty acid transport into mitochondria for energy production, it helps optimize fat oxidation during exercise, potentially improving endurance and reducing fatigue. Research indicates L-Carnitine supplementation may decrease post-exercise recovery time, reduce muscle damage, and enhance oxygen utilization during physical activity. This makes it particularly valuable for endurance athletes, bodybuilders, and those engaging in high-intensity training regimens seeking to optimize performance and body composition.
Cardiovascular Health Maintenance
L-Carnitine Base offers substantial benefits for cardiovascular health by supporting optimal heart function and energy metabolism. Research demonstrates its potential to improve cardiac performance by enhancing myocardial energy production, reducing oxidative stress, and supporting healthy lipid profiles. L-Carnitine supplementation has been associated with improvements in exercise tolerance in patients with cardiac conditions, reduced inflammation markers, and better vascular function. For individuals concerned with heart health or those managing existing cardiovascular conditions, L-Carnitine represents a science-backed nutritional intervention to support overall cardiac wellness.
Weight Management Support
L-Carnitine Base plays a significant role in weight management programs by enhancing the body’s fat-burning capabilities. As a key facilitator of fatty acid metabolism, it helps convert stored body fat into usable energy, potentially increasing the efficiency of weight loss efforts when combined with proper diet and exercise. Studies suggest L-Carnitine may help reduce fat mass, increase lean muscle retention, and improve body composition metrics. Its ability to support metabolic function makes it a popular supplement ingredient in comprehensive weight management formulations.
L-Carnitine Base Powder Manufacturing Process
Key Manufacturing Steps
- Starting Material: S,R-Epichlorohydrine (racemic mixture)
- Stereoselective Processing: Hydrolytic kinetic resolution separates S-isomer (>99% purity)
- Intermediate Formation: S-epichlorohydrine converts to L-Carnitinenitrile chloride via trimethylamine reaction
- Hydrolysis Process: Controlled reaction with sodium hydroxide creates L-Carnitine
- Purification Sequence: Ion exchange chromatography removes sodium chloride
- Final Processing: Concentration, drying, and crystallization yield L-Carnitine Base
- Refinement: Recrystallization and micronization achieve 99% pure final product
L-Carnitine Base Benefits
Enhanced Energy Production
• Transports fatty acids into mitochondria for conversion to energy • Improves cellular energy production efficiency • Reduces fatigue during physical activity • Enhances ATP production during exercise • Optimizes energy substrate utilization
Athletic Performance Support
• Increases endurance and exercise capacity • Reduces exercise-induced muscle damage • Accelerates post-workout recovery time • Delays onset of muscle fatigue • Improves oxygen utilization during high-intensity workouts
Weight Management
• Facilitates fat metabolism and burning • Supports healthy body composition • Enhances weight loss when combined with diet and exercise • Helps maintain lean muscle mass during caloric restriction • Improves metabolic flexibility
Cardiovascular Health
• Supports heart muscle function • Promotes healthy blood lipid profiles • Reduces oxidative stress in cardiovascular tissues • Improves exercise tolerance in heart patients • Supports vascular endothelial health
Cognitive Function
• Provides neuroprotective benefits • Supports brain energy metabolism • Enhances mental clarity and focus • Promotes healthy brain aging • Supports mitochondrial function in neural cells
Metabolic Health
• Improves insulin sensitivity • Supports balanced blood glucose levels • Enhances metabolic rate • Assists with carbohydrate metabolism • Promotes overall metabolic wellness
Recovery Benefits
• Reduces exercise-induced inflammation • Decreases muscle soreness after intense activity • Accelerates glycogen replenishment • Supports overall exercise recovery • Diminishes markers of exercise-induced stress
Where to buy L-Carnitine Base bulk powder?
Looking for premium-quality L-Carnitine Base bulk powder from a reliable source? ProVita Biotech stands as China’s leading manufacturer and supplier of pharmaceutical-grade L-Carnitine Base powder. With our advanced production facilities and stringent quality control systems, we deliver L-Carnitine Base bulk powder that meets or exceeds international standards for purity (≥98%) and efficacy.
At ProVita Biotech, we specialize in: • Large-volume L-Carnitine Base bulk powder supply for manufacturers • Custom formulation services for supplement brands • Consistent batch-to-batch quality of L-Carnitine Base powder • Competitive pricing for bulk L-Carnitine Base orders • Fast global shipping with comprehensive logistics support
Our L-Carnitine Base bulk powder undergoes rigorous testing for identity, purity, and potency, supported by comprehensive documentation and certificates of analysis. We maintain full compliance with GMP standards and international regulatory requirements, ensuring you receive only the highest quality L-Carnitine Base for your formulations.
Contact ProVita Biotech today to request samples, discuss your L-Carnitine Base bulk powder requirements, or place an order. Partner with the trusted industry leader for all your L-Carnitine Base supply needs and experience our commitment to excellence, reliability, and customer satisfaction.
FAQs
Carnitine refers to both D and L isomers collectively, while L-Carnitine specifically denotes the biologically active "levo" isomer that ProVita Biotech produces. Only L-Carnitine is functionally effective in human metabolism, which is why we exclusively manufacture this form to ensure maximum efficacy in your formulations.
L-Carnitine Base is the pure, free-form version with approximately 100% L-Carnitine content, whereas L-Carnitine Tartrate is a salt form containing roughly 68% L-Carnitine bound to tartaric acid. Our L-Carnitine Base offers greater formulation flexibility and higher L-Carnitine content per gram, making it cost-effective for manufacturers requiring pure active ingredient.
These terms are often used interchangeably in our catalog. L-Carnitine Base specifically refers to our pure, free-form L-Carnitine powder without additional salt compounds, distinguishing it from derivatives like L-Carnitine Tartrate or Acetyl-L-Carnitine. ProVita Biotech's L-Carnitine Base is ideal for formulators seeking maximum potency and versatility.
Our L-Carnitine Base is produced through an advanced chemical synthesis process involving chiral separation to ensure optical purity, followed by multiple purification steps and crystallization. This proprietary process guarantees consistent 98%+ purity and full compliance with pharmacopoeia standards for all our L-Carnitine Base bulk powder.
ProVita Biotech's L-Carnitine Base is manufactured in our ISO 9001, ISO 22000, and cGMP-certified facilities. We provide comprehensive documentation including Certificate of Analysis (COA), Certificate of Origin, HPLC analysis reports, and stability data. Our L-Carnitine Base meets USP, EP, and JP pharmacopoeia standards, with full allergen, non-GMO, and BSE/TSE-free certifications.
Each batch of our L-Carnitine Base undergoes rigorous testing via HPLC, FTIR spectroscopy, optical rotation analysis, and heavy metal screening. Our in-house and third-party testing protocols ensure consistent 98-102% purity, correct isomeric composition, and compliance with all regulatory specifications before release to customers.
ProVita Biotech's standard MOQ for L-Carnitine Base is 25kg. However, we offer flexibility for new clients with 5-10kg trial orders to evaluate our product quality. For established partners with regular purchasing schedules, we can accommodate customized ordering arrangements.
Our L-Carnitine Base bulk pricing operates on a tiered system based on volume, starting at $XX/kg for 25-100kg orders, with significant discounts available for larger quantities. We offer competitive pricing advantages for quarterly or annual supply contracts. Contact our sales team for a detailed quotation tailored to your specific requirements.
ProVita Biotech maintains substantial L-Carnitine Base inventory, allowing 2-4 days fulfillment for standard orders under 100kg. Custom or larger orders typically require 1-2 weeks production time. We offer expedited production services for time-sensitive projects and can develop specialized JIT inventory programs for regular customers.
Yes, we provide complete OEM/ODM services including custom formulation, blending with other active ingredients, specific particle size adjustment, and packaging customization. Our R&D team can develop specialized L-Carnitine Base formulations to meet your specific application requirements, stability needs, or delivery system specifications.