L-Tyrosine Powder
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What is L-Tyrosine?
L-Tyrosine (CAS Number: 60-18-4), also known as 4-hydroxyphenylalanine or Tyrosine or (S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid, is a non-essential amino acid with the molecular formula C9H11NO3 and a molecular weight of 181.19 g/mol. This naturally occurring compound can be found in various botanical sources including soybeans, nuts, seeds, dairy products, and certain high-protein foods. Commercial L-Tyrosine typically appears as a white to off-white crystalline powder with specifications generally requiring purity levels exceeding 99%. When ingested, L-Tyrosine demonstrates moderate bioavailability of approximately 70-80%, with absorption primarily occurring in the small intestine and subsequently crossing the blood-brain barrier to support neurotransmitter production. Provita Biotech stands as the leading bulk L-Tyrosine powder supplier in China, providing high-quality pharmaceutical and nutritional grade material to global markets for use in dietary supplements, functional foods, and pharmaceutical applications.
L-tyrosine vs N-acetyl L-tyrosine
When comparing L-Tyrosine and N-Acetyl L-Tyrosine (NALT), L-Tyrosine is generally considered more effective for most applications despite common marketing claims. While NALT has better solubility in water, research indicates L-Tyrosine has superior bioavailability for raising tyrosine levels in the brain. L-Tyrosine crosses the blood-brain barrier more efficiently and provides better value for money. Most clinical studies showing cognitive benefits have used regular L-Tyrosine rather than NALT. Unless water solubility is the primary concern (such as for liquid supplements), standard L-Tyrosine is typically the better choice for cognitive enhancement, stress reduction, and overall effectiveness.
| Feature | L-Tyrosine | N-Acetyl L-Tyrosine (NALT) |
|---|---|---|
| CAS Number | 60-18-4 | 537-55-3 |
| Other Names | 4-hydroxyphenylalanine, Tyrosine | NALT, N-acetyltyrosine |
| Molecular Formula | C₉H₁₁NO₃ | C₁₁H₁₃NO₄ |
| Molecular Weight | 181.19 g/mol | 223.23 g/mol |
| Appearance | White to off-white crystalline powder | White crystalline powder |
| Purity | Typically ≥99% | Typically ≥98% |
| Solubility | Poorly soluble in water | Highly soluble in water |
| Bioavailability | Moderate (70-80%), but more efficient at crossing the blood-brain barrier | High water solubility but less effective at increasing brain tyrosine levels |
| Potency | More potent for neurological effects | Less potent for neurological effects despite marketing claims |
| Half-life | 2-3 hours | Shorter; rapidly deacetylated in the body |
| Stability | Stable under normal conditions | More stable in solution |
| Popularity | More common in clinical research | Popular in liquid supplements due to solubility |
| Pricing | Less expensive per effective dose | More expensive per effective dose |
| Main Benefits | • Cognitive enhancement under stress • Mood support • Mental performance • Thyroid hormone production • Catecholamine precursor | • Same potential benefits as L-Tyrosine • Better for liquid formulations • Potentially less GI discomfort |
| Dosage Range | 500-2000 mg, typically 1-3 times daily | 600-2500 mg, typically 1-3 times daily |
| Research Support | More extensive clinical research background | Fewer dedicated clinical studies |
| Best Used For | Cognitive formulations, stress management, physical performance | Liquid supplements, individuals with sensitivity to regular L-Tyrosine |
L-Tyrosine Powder COA
ProVita Biotech’s L-Tyrosine Powder (non-animal source/vegan) demonstrates an assay of 99.2% (dry basis), surpassing the USP/EP specification range of 98.5%–101.5% for optimal purity. Heavy metals, including lead, arsenic, mercury, and cadmium, are well below allowable limits, ensuring safety and quality. Residual solvents also meet USP <467> requirements, confirming minimal solvent content. These comprehensive results verify that ProVita Biotech’s L-Tyrosine Powder meets international standards and has undergone third-party testing to guarantee premium quality.
Application
Cognitive Support
L-Tyrosine aids in the production of neurotransmitters like dopamine and norepinephrine, helping enhance focus, mental clarity, and overall brain function.
Stress Management
By supporting adrenal hormone synthesis, L-Tyrosine can promote a balanced stress response and may help reduce feelings of fatigue and tension.
Thyroid Health
As a precursor to thyroid hormones, L-Tyrosine contributes to healthy metabolic activity and energy levels, making it vital for overall well-being.
L-Tyrosine Powder Manufacturing Process
1. Bacterial Strain Preparation
- The process begins with the preparation of Corynebacterium glutamicum, a non-pathogenic bacterial strain specifically selected for L-Tyrosine production
- The bacterial strain is maintained under controlled conditions to ensure genetic stability and production efficiency
2. Culture Enlargement
- The initial bacterial culture is progressively expanded in a series of fermentation vessels of increasing size
- Sterile air is continuously supplied to maintain aerobic conditions optimal for growth
- Carefully controlled temperature, pH, and nutrient levels ensure robust bacterial growth
3. Fermentation
- The main fermentation occurs in large-scale bioreactors
- Glucose serves as the primary carbon source for the bacteria
- Compressed air is introduced to maintain optimal dissolved oxygen levels
- The fermentation process is closely monitored for:
- pH (maintained between 6.8-7.2)
- Temperature (optimal at 30-32°C)
- Dissolved oxygen levels
- Nutrient consumption rates
4. Fermentation Solution Processing
- Once fermentation is complete, the solution contains high concentrations of L-Tyrosine
- The fermentation broth undergoes initial processing to separate bacterial cells from the solution
5. Micro-filtration and Sterilization
- The solution passes through micro-filtration systems to remove bacterial cells and larger impurities
- Sterilization eliminates any remaining viable microorganisms
- This step ensures the purity of the subsequent crystallization process
6. Crude Crystallization
- The filtered solution undergoes initial crystallization to separate L-Tyrosine from the liquid medium
- Temperature and pH are precisely controlled to optimize crystal formation
- This step yields crude L-Tyrosine crystals
7. Solvent-out Crystallization with Activated Carbon Treatment
- The crude crystals are dissolved in a suitable solvent
- Activated carbon treatment is performed to remove color impurities and trace contaminants
- Secondary crystallization (solvent-out) produces higher purity L-Tyrosine crystals
- This critical purification step significantly increases product purity
8. Centrifugal Separation, Drying and Packaging
- The purified crystals are separated from the solution using centrifugation
- The crystals undergo controlled drying under specific temperature and humidity conditions
- The dried L-Tyrosine powder is precisely weighed and packaged in appropriate containers
- Each batch is labeled with production information and quality control data
9. Quality Control and Testing
- The finished product undergoes rigorous quality testing including:
- Purity analysis (ensuring 99% purity)
- Microbiological testing
- Heavy metal analysis
- Residual solvent testing
- Moisture content verification
- Third-party laboratory testing confirms compliance with international standards
L-Tyrosine Benefits
- Boosts Mental Clarity and Focus: L-Tyrosine supports the production of dopamine and norepinephrine, helping sharpen concentration.
- Helps Reduce Stress and Fatigue: By aiding adrenal hormone synthesis, L-Tyrosine may support a balanced response to stress.
- Promotes Healthy Thyroid Function: As a precursor to thyroid hormones, L-Tyrosine assists in maintaining optimal metabolism and energy.
- Enhances Mood Balance: L-Tyrosine aids neurotransmitter regulation, contributing to stable, positive mood states.
- Essential for Protein Synthesis: L-Tyrosine is a key amino acid for building proteins, promoting overall cellular health and recovery.
Where to buy L-Tyrosine bulk powder?
Looking for premium L-Tyrosine bulk powder? ProVita Biotech stands as China’s leading supplier of pharmaceutical-grade L-Tyrosine powder with over 15 years of manufacturing expertise. Our L-Tyrosine bulk powder meets strict USP/EP standards with 99%+ purity, available in commercial quantities from 1kg to multi-ton orders at competitive factory-direct pricing. As a GMP-certified facility, we provide comprehensive documentation including COA, MSDS, and full traceability for each L-Tyrosine batch. Health supplement manufacturers, pharmaceutical companies, and nutrition brands worldwide trust our consistent L-Tyrosine supply chain and reliable delivery timelines. Contact our L-Tyrosine specialists today for bulk powder quotations, technical specifications, or custom formulation support. ProVita Biotech – Your trusted partner for high-quality L-Tyrosine bulk powder.
FAQs
L-Tyrosine is a precursor to neurotransmitters (dopamine, norepinephrine) that enhances focus during stress, while L-Theanine promotes relaxation without sedation. Many brands combine both in their formulations, with our L-Tyrosine showing excellent synergistic effects with L-Theanine at a ratio of 2:1. ProVita Biotech supplies both amino acids at pharmaceutical grade (99%+ purity).
For most dietary supplement and protein formulations, our standard L-Tyrosine offers superior cost-effectiveness and bioavailability. While N-Acetyl L-Tyrosine provides better water solubility for liquid applications, research indicates pure L-Tyrosine crosses the blood-brain barrier more efficiently, making it our recommended form for most commercial products.
L-Tyrosine is a polar molecule due to its hydroxyl, carboxyl, and amino groups, though its aromatic ring contributes some nonpolar character. This amphipathic nature affects its formulation behavior—our technical team provides stability guidance for various delivery systems including capsules, tablets, and powdered blends.
L-Tyrosine demonstrates limited water solubility (approximately 0.45 g/L at 25°C) due to its partially hydrophobic aromatic side chain. ProVita Biotech's micronized L-Tyrosine grade offers improved dispersion characteristics for product developers working with liquid or suspension formulations.
Our L-Tyrosine is frequently incorporated into pre-workout and sports nutrition formulations to enhance focus, reduce mental fatigue during intense exercise, support catecholamine production during physical stress, and aid in post-workout recovery. Our technical team can recommend optimal dosages for specific application types.
While L-Tyrosine occurs naturally in protein-rich foods (cheese, soybeans, poultry, fish), supplemental L-Tyrosine provides precisely controlled amounts for consistent formulation. ProVita Biotech's synthetic L-Tyrosine matches the molecular structure of food-derived tyrosine with superior purity specifications.
Our L-Tyrosine is produced using enzymatic fermentation with subsequent purification through crystallization, guaranteeing 99%+ purity. This process ensures consistent particle size distribution, low heavy metal content (<10ppm), and minimal microbial load, making it ideal for pharmaceutical and premium supplement applications.
Every L-Tyrosine shipment includes a comprehensive documentation package: Certificate of Analysis (CoA), Certificate of Origin, GMP certification, ISO 9001 compliance documentation, allergen statement, non-GMO declaration, BSE/TSE-free certification, and full lot traceability records.
Our minimum order quantity for standard L-Tyrosine is 25kg, with scaled pricing advantages at 100kg, 500kg, and 1-ton quantities. For OEM/private label customers, minimum quantities start at 500kg per formulation.
Current bulk pricing ranges from $12-18/kg depending on volume, purity specifications, and packaging requirements. We offer competitive direct manufacturer pricing with flexible terms for established nutraceutical and pharmaceutical partners.
Yes, ProVita Biotech provides comprehensive OEM services including custom L-Tyrosine blends, specialized particle sizes, and finished product manufacturing. Our R&D team can develop exclusive L-Tyrosine formulations with documented stability studies and marketing support materials.