PhosphatidylSerine Powder 20%
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What is PhosphatidylSerine?
PhosphatidylSerine (PS) is a phospholipid component that naturally occurs in cell membranes, particularly abundant in brain tissue, with CAS number 51446-62-9. Also known as 1,2-diacyl-sn-glycero-3-phospho-L-serine or PS, it has a molecular formula of C₁₃H₂₄NO₁₀P and a molecular weight of approximately 385.36 g/mol. Foods naturally high in PS include organ meats, white beans, soy products, and egg yolks, though commercial PS is typically extracted from soybean (glycine max) or sunflower (helianthus annuus) sources, available in various specifications including 20%, 50%, and 70% powder concentrations. The substance appears as an off-white to slightly yellowish fine powder with good bioavailability when administered orally, showing significant absorption rates and ability to cross the blood-brain barrier. Provita Biotech stands as the leading bulk PhosphatidylSerine powder supplier in China, offering premium quality PS in multiple specifications derived from different plant sources including both soybean and sunflower extracts, catering to diverse manufacturing requirements.
Phosphatidylcholine vs Phosphatidylserine
While both Phosphatidylcholine (PC) and Phosphatidylserine (PS) are essential phospholipids with significant health benefits, they serve different biological functions. PS is generally considered more effective for cognitive enhancement and neurological health, with stronger clinical evidence supporting its use in memory improvement and stress reduction. Meanwhile, PC excels in liver health applications and has broader availability in dietary sources. The choice between these compounds ultimately depends on specific health goals – PS for brain function and stress management, or PC for liver support and general cell membrane integrity.
| Property | Phosphatidylcholine (PC) | Phosphatidylserine (PS) |
|---|---|---|
| CAS Number | 8002-43-5 (Lecithin) / 63-89-8 (Pure PC) | 51446-62-9 |
| Other Names | Lecithin, 1,2-diacyl-sn-glycero-3-phosphocholine | 1,2-diacyl-sn-glycero-3-phospho-L-serine, PS |
| Molecular Formula | C₄₂H₈₄NO₈P (typical) | C₁₃H₂₄NO₁₀P |
| Molecular Weight | ~760 g/mol (varies with fatty acid composition) | ~385.36 g/mol |
| Appearance | Yellow to brown waxy solid or powder | Off-white to slightly yellowish fine powder |
| Purity | Available in 30%-98% concentrations | Available in 20%, 50%, 70% concentrations |
| Bioavailability | Moderate oral bioavailability | Good oral bioavailability; crosses blood-brain barrier effectively |
| Potency | Moderate for liver functions | High for cognitive functions |
| Half-life | 60-90 minutes | 20-30 hours in brain tissue |
| Stability | Stable at room temperature; sensitive to oxidation | More stable than PC; less susceptible to oxidation |
| Popularity | Widely used in supplements and food | Growing popularity in nootropic and anti-aging supplements |
| Pricing | Generally more affordable | Typically more expensive than PC |
| Main Benefits | Liver health, cell membrane integrity, fat metabolism | Cognitive enhancement, memory improvement, stress reduction |
| Natural Sources | Egg yolks, soybeans, sunflower, liver | Lower concentrations in foods; highest in brain tissue |
| Commercial Sources | Primarily soy and sunflower | Typically soy and sunflower extracts |
| Research Backing | Extensive for liver conditions | Strong evidence for cognitive benefits |
| Typical Dosage | 500-2000 mg daily | 100-400 mg daily |
| Safety Profile | High safety margin; well-tolerated | Generally safe with few reported side effects |
| Primary Function | Component of cell membranes; supports liver | Signaling molecule in cell membranes, especially in brain |
| Regulatory Status | GRAS (Generally Recognized As Safe) | Generally recognized as safe supplement ingredient |
PhosphatidylSerine Powder COA
ProVita Biotech’s PhosphatidylSerine powder 20% (Batch No. 20240802) exceeds quality specifications with a 23.23% assay result, demonstrating premium purity. The product shows exceptional safety with heavy metals testing well below international limits (<10PPM total heavy metals, with specific testing for arsenic, lead, cadmium, and mercury all confirming compliance). No detectable residual solvents are present, while microbial testing confirms negative results for E.coli, Salmonella, and Staphylococcus. This Certificate of Analysis verifies that ProVita Biotech’s PhosphatidylSerine powder meets or exceeds all international standards through rigorous third-party testing using advanced methodologies, including HPLC and ICP-MS, underscoring ProVita Biotech’s unwavering commitment to providing supplement manufacturers and distributors with consistently safe, high-quality ingredients they can trust for their formulations.
Application
Brain Health
Phosphatidylserine (PS) stands as a clinically-backed nootropic that enhances cognitive function across all age groups. This brain-enriched phospholipid maintains neuronal membrane integrity and facilitates neurotransmitter release, directly supporting memory formation and recall. Research shows PS supplementation improves attention, concentration, and information processing, with studies demonstrating particular efficacy in age-related cognitive decline. At dosages of 100-300mg daily, PS supplementation can noticeably improve verbal memory and name recall in older adults while enhancing mental performance during demanding cognitive tasks in younger individuals.
Cortisol Regulation
Phosphatidylserine demonstrates remarkable effectiveness in modulating the body’s stress response by helping regulate cortisol levels. This adaptogenic quality makes PS particularly valuable for individuals experiencing chronic stress, athletes undergoing intense training, and those with cortisol-related sleep disturbances. Clinical research indicates PS supplementation can significantly reduce serum cortisol levels during stressful situations, improving perceived well-being and emotional stability. By blunting excessive cortisol production, PS helps prevent stress-induced cognitive impairment, supports immune function, and promotes healthier sleep patterns.
Athletic Performance
Athletes increasingly turn to Phosphatidylserine for its dual benefits in performance enhancement and recovery acceleration. PS supplementation has been shown to decrease exercise-induced muscle damage, reduce post-workout soreness, and shorten recovery times between training sessions. By regulating cortisol levels during intense physical activity, PS helps preserve muscle tissue and optimize testosterone-to-cortisol ratios. Studies with endurance athletes demonstrate PS can improve exercise capacity, delay fatigue, and enhance recovery markers. This phospholipid’s ability to support both mental focus during competition and physical recovery afterward makes it a comprehensive performance supplement.
PhosphatidylSerine Powder Manufacturing Process
ProVita Biotech employs a sophisticated enzymatic transphosphatidylation process to produce its premium 20% PhosphatidylSerine (PS) powder. The manufacturing begins with high-quality soy lecithin as the primary raw material, which serves as the phospholipid donor in the reaction.
The process starts by combining soy lecithin with an aqueous solution containing L-Serine and phospholipase enzyme in the presence of specific salts that optimize the reaction conditions. During this enzymatic reaction, the phospholipase facilitates the exchange of the head group of phosphatidylcholine in soy lecithin with L-Serine, effectively converting it to phosphatidylserine.
After the reaction is complete, the resulting soy lecithin-phosphatidylserine complex undergoes a thorough purification process to remove unreacted materials, enzymes, and other impurities. This purification step is critical in achieving the target 20% concentration of phosphatidylserine in the final product.
The purified material then enters a carefully controlled drying phase conducted in a GMP-certified facility, followed by a precision smashing process that creates the fine yellow powder characteristic of the final product. Throughout manufacturing, quality control measures are implemented, including HPLC analysis to verify phosphatidylserine content and purity.
The finished powder is packaged under strict GMP conditions and stored in a controlled warehouse environment. Each batch undergoes comprehensive testing to ensure it meets or exceeds international standards for heavy metals (<10PPM), microbial content (negative for pathogens), and other quality parameters as verified by rigorous third-party testing. The final product consistently achieves 23.23% phosphatidylserine content, exceeding the 20% specification and demonstrating ProVita Biotech’s commitment to delivering superior quality ingredients for the supplement industry.
PhosphatidylSerine PS Benefits
Cognitive Enhancement
- Improves memory formation and recall in both young and elderly individuals
- Enhances focus, concentration, and attention span during demanding mental tasks
- Supports learning ability and information processing speed
- Helps prevent age-related cognitive decline and memory loss
- Maintains neuronal membrane integrity essential for optimal brain function
Stress Management
- Reduces cortisol levels during physical and mental stress
- Improves mood and emotional stability during stressful periods
- Promotes better stress recovery and adaptation
- Helps regulate the hypothalamic-pituitary-adrenal (HPA) axis
- Supports healthier sleep patterns by normalizing stress hormone levels
Athletic Performance
- Speeds up post-exercise recovery time
- Reduces exercise-induced muscle soreness and damage
- Decreases perception of exertion during intense training
- Improves endurance and delays exercise fatigue
- Helps maintain optimal testosterone-to-cortisol ratio
Brain Health
- Supports cell membrane fluidity in brain neurons
- Facilitates neurotransmitter release and nerve signal transmission
- Protects brain cells from oxidative damage
- Promotes healthy brain aging and neuroplasticity
- May help reduce brain inflammation
General Wellness
- Supports healthy cell membrane function throughout the body
- Enhances immune system response and regulation
- Improves glucose metabolism in the brain
- Supports cardiovascular health by maintaining healthy cell membranes
- May help balance hormone production and signaling
ADHD & Cognitive Disorders
- Shows promise in managing ADHD symptoms in children and adults
- Improves attention and reduces impulsivity in individuals with ADHD
- Supports cognitive function in various neurological conditions
- May enhance the effectiveness of conventional ADHD treatments
- Provides a natural approach to cognitive support
Where to buy PhosphatidylSerine Powder bulk powder?
When sourcing premium PhosphatidylSerine bulk powder, ProVita Biotech is China’s foremost manufacturer and supplier. Our facility produces pharmaceutical-grade PS powder in multiple concentrations (20%, 50%, and 70%) derived from soybean and sunflower extracts to meet diverse manufacturing requirements.
Why Source PS Powder from ProVita Biotech?
- Guaranteed Purity – All PhosphatidylSerine bulk powder undergoes rigorous testing with 20% purity certification
- Competitive Factory-Direct Pricing – Eliminate middlemen and access wholesale PS powder at manufacturer rates.
- Multiple Specifications – Choose from 20%, 50%, or 70% PhosphatidylSerine concentrations based on your formulation needs
- Source Options – Both soy-derived and sunflower-derived PhosphatidylSerine powder available
- Free Samples – Request complimentary PS powder samples for evaluation before placing bulk orders
- Certificate of Analysis – Each PhosphatidylSerine shipment includes comprehensive documentation
- Custom Packaging – Flexible packaging options for PhosphatidylSerine bulk orders (1kg, 5kg, 25kg)
How to Order PhosphatidylSerine from ProVita Biotech
Purchasing bulk PhosphatidylSerine powder is straightforward – contact our dedicated export team through our website form or direct email. Specify your desired PS specification (20%, 50%, or 70%), quantity requirements, and preferred plant source. Our representatives will promptly provide PhosphatidylSerine pricing, availability, and shipping options to destinations worldwide.
Choose ProVita Biotech for guaranteed quality PhosphatidylSerine powder, competitive pricing, and exceptional customer service from China’s premier phospholipid supplier.
FAQs
ProVita's PhosphatidylSerine (PS) delivers three core benefits that drive its popularity in premium formulations: cognitive enhancement (memory, focus, and learning support), stress management (cortisol regulation), and athletic recovery (reduced muscle soreness and improved endurance). Our pharmaceutical-grade PS is particularly valued for its clinically-supported cognitive applications, making it essential for nootropic and anti-aging formulations.
While both support cognitive function, they work through different mechanisms. PhosphatidylSerine primarily enhances neuronal membrane integrity and neurotransmitter function, excelling in memory enhancement and stress reduction. Citicoline (CDP-Choline) focuses on acetylcholine production and brain energy metabolism. Many of our clients combine both in premium formulations for complementary cognitive benefits, with PS typically dosed at 100-300mg and Citicoline at 250-500mg daily.
PS occurs naturally in foods like soy, white beans, egg yolks, and organ meats, but in concentrations far too low for therapeutic effects. A serving of organ meat contains approximately 3mg of PhosphatidylSerine, while clinical benefits typically require 100-300mg daily. This significant gap explains why our extracted and concentrated PS powder (20%-70%) is essential for effective supplement formulations.
Our clients frequently pair PhosphatidylSerine with complementary nootropics including:
- Bacopa Monnieri (enhances memory alongside PS)
- Ginkgo Biloba (improves cerebral circulation)
- Lion's Mane Mushroom (supports nerve growth factor)
- Rhodiola Rosea and L-Theanine (amplify PS's stress-management properties)
- Omega-3 DHA/EPA (enhance phospholipid integration)
- B Vitamins (particularly B12, folate, and B6)
These combinations maximize cognitive benefits while addressing multiple neurological pathways.
ProVita's PS powder demonstrates excellent stability in capsules and tablets with 24-36 month shelf life when properly stored. For liquid formulations, we recommend our specialized liposomal PS which maintains stability in suspension. Our R&D team provides formulation guidelines for ensuring PS stability across various pH levels, temperature ranges, and delivery systems to maximize product efficacy and shelf life.
We manufacture three primary PhosphatidylSerine concentrations:
- 20% PS Powder (most economical, ideal for higher-dose formulations)
- 50% PS Powder (our most popular specification, balancing potency and value)
- 70% PS Powder (highest concentration for premium products with limited capsule space)
All specifications are available from both soybean and sunflower sources, with consistent batch-to-batch profiles.
ProVita employs a proprietary enzymatic conversion process starting with lecithin extracted from either soybean or sunflower. This specialized technique ensures higher purity and bioavailability than chemical synthesis methods. Our process includes multiple filtration and purification steps in our ISO-certified facility, resulting in pharmaceutical-grade PS with minimal impurities and consistent phospholipid profiles.
All ProVita PhosphatidylSerine shipments include:
- Certificate of Analysis (CoA) with full specification testing
- ISO 9001:2015 manufacturing certification
- Non-GMO certification (for both soy and sunflower sources)
- Allergen statement
- Heavy metal testing documentation
- Microbiological safety certification
- Kosher and Halal certificates available upon request
Our minimum order quantities are structured to accommodate various business needs:
- Trial Order: 1kg (available for all PS specifications)
- Standard Order: 5kg (most economical shipping rate per kg)
- Bulk Order: 25kg+ (qualifies for preferential pricing)
We can occasionally accommodate smaller sample quantities for formulation testing.
Yes, ProVita Biotech provides comprehensive OEM/ODM services including custom PS-based formulations, blending with complementary ingredients, and finished product manufacturing in various delivery formats. Our R&D team can develop unique PS combinations optimized for specific cognitive or athletic applications, with complete packaging and labeling services available.
We ship PS worldwide via express courier (DHL/FedEx) for smaller orders and sea freight for bulk shipments. All exports include complete documentation for customs clearance, including CoA, commercial invoice, packing list, and health certificates. Our logistics team manages regulatory requirements for each destination country, ensuring smooth customs clearance for PhosphatidylSerine shipments globally.
For detailed bulk pricing, please contact our sales team via email or phone call. You'll get a quotation within 8 hours.