Bulk Vitamin K2 PowderSupplier in China
ProVita Biotech supplies high-quality Vitamin K2 powder, including MK-7 and MK-4 forms, for dietary supplements, functional foods, capsules, tablets, softgels, gummies, and custom formulas.
- Vitamin K2 MK-7 powder with available 1.0% and 1.3% specifications
- Bulk supply and OEM support
- COA, MSDS, specification sheet, product flow chart,
- 500 tons of vitamin K2 Ingredient export Annually
Home / Products / Specialty Ingredients / Wholesale Vitamin K2 Powder 99%
What Is Vitamin K2?
Vitamin K2 is a fat-soluble vitamin and a member of the vitamin K family, also known as menaquinone, with common supplement forms including Vitamin K2 MK-4 and Vitamin K2 MK-7. NIH explains that vitamin K includes phylloquinone, known as Vitamin K1, and menaquinones, known as Vitamin K2, with MK-4, MK-7, and MK-9 among the most studied menaquinones. Vitamin K2 can be found in fermented foods and some animal-based foods, while natural Vitamin K2 MK-7 is commonly produced through natto-related fermentation. MK-7 is widely used in modern supplements because of its longer side chain, higher stability, and longer retention time compared with MK-4. ProVita Biotech supplies Vitamin K2 MK-7 powder with CAS No. 2124-57-4, other names including Menaquinone-7, Vitamin MK-7, Vitamin K2 MK-7, and all-trans MK-7, molecular formula C46H64O2, and molecular weight 649.1. For high-purity Vitamin K2 material, the specification can be 99% HPLC, with a white crystalline powder appearance, practically insoluble in water, fat-soluble, and suitable for bioavailable supplement formulations. ProVita also offers commercial MK-7 powder grades such as 1.0% and 1.3% all-trans MK-7 in MCC powder, with a white to pale yellow powder appearance. Standard bulk packaging can be 25kg/drum, with customized packaging available for different projects. ProVita Biotech is a leading bulk Vitamin K2 powder supplier in China, supporting raw material supply, private label solutions, and OEM supplement manufacturing, including Vitamin K2 capsules, tablets, softgels, gummies, and custom D3 K2 formulas.
Vitamin K2 Forms: MK-7 vs MK-4
For most modern dietary supplement products, Vitamin K2 MK-7 is usually the better commercial choice because it has a longer half-life, good absorption, lower dosage requirement, and stronger market popularity in bone health, heart health, and Vitamin D3 K2 formulas. MK-4 is still a well-known form of Vitamin K2, but it is often used at higher dosage levels and is more common in specific formulas rather than mainstream daily K2 supplements. NIH notes that Vitamin K2 is available in supplement forms such as MK-4 and MK-7, and that one study found both phytonadione and MK-7 were well absorbed, while MK-7 had a longer half-life. ProVita Biotech’s popular commercial specifications include K2 MK-7 1.0% in MCC Powder and K2 MK-7 1.3% in MCC Powder, both with all-trans MK-7 assay, white to pale yellow powder appearance, and COA/specification support.
| Item | Vitamin K2 MK-7 | Vitamin K2 MK-4 |
|---|---|---|
| Full Name | Menaquinone-7 | Menaquinone-4 |
| Common Names | Vitamin K2 MK-7, MK-7, Menaquinone-7, all-trans MK-7, Vitamin MK-7 | Vitamin K2 MK-4, MK-4, Menaquinone-4, Menatetrenone |
| CAS Number | 2124-57-4 | 863-61-6 |
| Molecular Formula | C46H64O2 | C31H40O2 |
| Molecular Weight | 649.1 g/mol | 444.65 g/mol |
| Appearance | Usually yellow oil or powder after dilution/carrier processing; ProVita MK-7 in MCC powder is white to pale yellow powder | Usually yellow to orange crystalline powder or oil-like material depending on purity and form |
| Food Sources | Mainly fermented foods, especially natto; also found in some fermented cheese | Animal-based foods such as meat, poultry, eggs, dairy, liver, and some animal tissues |
| Production Source | Often produced by natto-related fermentation, then purified and converted into oil or powder form | Commonly produced by synthesis, though MK-4 also exists naturally in animal foods |
| Common Supplement Form | Capsules, tablets, softgels, drops, gummies, powder blends, D3 K2 formulas | Capsules, tablets, softgels, and some high-dose K2 products |
| Popular Specifications | 0.1%, 0.2%, 1%, 1.3%, 2%, 5%, 98%, 99%; oil and powder forms available | 1%, 5%, 10%, 98%, 99%; powder or oil forms depending on application |
| ProVita Popular Specs | K2 MK-7 1.0% in MCC Powder and K2 MK-7 1.3% in MCC Powder | Custom sourcing or formulation support available depending on buyer requirements |
| Purity | Commercial powder grades often use carriers such as MCC and MCT; high-purity MK-7 may reach 98% to 99% by HPLC | High-purity MK-4 can commonly reach 98% to 99% by HPLC |
| Bioavailability | Generally considered highly bioavailable in supplement form; long-chain MK-7 may have better absorption and longer circulation than some other forms | Bioavailable but shorter acting, usually cleared faster from the body |
| Half-Life | Longer half-life; often described as suitable for once-daily supplement formulas | Shorter half-life; may require higher or more frequent dosage in some formulas |
| Dosage Level | Usually microgram-level, commonly 45 mcg, 90 mcg, 100 mcg, 120 mcg, 180 mcg, or 200 mcg per serving | Often used at much higher levels, commonly in milligram-level formulas depending on market and regulatory positioning |
| Potency in Formulation | Strong commercial potency at low dosage, especially for daily bone and cardiovascular health supplements | Useful in specific K2 formulas but usually less efficient for low-dose daily supplements |
| Stability | Good stability when properly protected from light, oxygen, heat, and moisture; microencapsulation or MCC carrier can improve handling | Generally stable as a high-purity synthetic material, but still should be protected from light, heat, and oxidation |
| Solubility | Fat-soluble, practically insoluble in water; suitable for oil-based softgels, emulsions, and carrier-based powders | Fat-soluble, practically insoluble in water; suitable for oil systems and solid dosage forms |
| Main Benefits | Supports bone metabolism, calcium utilization, osteocalcin activation, cardiovascular wellness, and D3 K2 supplement positioning | Supports vitamin K-dependent proteins, bone metabolism, and specific K2 applications |
| Best Product Positioning | Daily bone health, heart health, healthy aging, menopause support, calcium magnesium D3 K2 formulas | Specialized K2 formulas, higher-dose formulas, and products where MK-4 is specifically requested |
| Market Popularity | Very popular in modern supplements, especially D3 K2 capsules, softgels, gummies, and drops | Known in the market, but generally less popular than MK-7 for mainstream daily supplement products |
| Pricing Range | Usually higher than MK-4 for high-purity material; wide market range depending on assay, all-trans content, carrier, source, and order quantity | Usually lower than high-purity MK-7, but pricing varies by purity, synthesis route, quality standard, and volume |
| General Bulk Price Trend | Low-percentage powder grades are more cost-effective for finished supplements; high-purity 98% to 99% MK-7 is much more expensive | 98% to 99% MK-4 is generally more affordable than high-purity MK-7, but requires higher dosage in many formulas |
| Formula Compatibility | Excellent for D3 K2, calcium K2, magnesium D3 K2, bone health gummies, softgels, tablets, and capsules | Suitable for tablets, capsules, and certain professional formulas |
| Buyer Recommendation | Best choice for most supplement brands looking for a popular, efficient, once-daily K2 ingredient | Choose when your formula specifically requires MK-4 or a higher-dose K2 concept |
Vitamin K2 MK-7 Certificate of Analysis(COA)
ProVita Biotech provides Vitamin K2 MK-7 COA support for two available commercial specifications: K2 MK-7 1.0% in MCC Powder and K2 MK-7 1.3% in MCC Powder, with custom specifications available according to buyer formulation needs. In the COA, the all-trans MK-7 assay is tested by USP method, with the 1.0% grade showing 1.1% result against 1.0% min, and the 1.3% grade showing 1.4% result against 1.3% min. Both grades conform to white to pale yellow powder appearance and characteristic odor. Key quality parameters include loss on drying 8.0% max, with actual result 2.58%, and residue on ignition 0.2% max, with actual result 0.049%. Heavy metal control includes heavy metals ≤10 ppm, arsenic ≤0.5 ppm, lead ≤0.5 ppm, cadmium ≤0.3 ppm, and mercury ≤0.1 ppm, with microbial limits covering aerobic plate count ≤1000 cfu/g, yeasts and molds ≤100 cfu/g, and negative results for E. coli, Salmonella, and Staphylococcus aureus. Testing methods include USP, GB5009.3, GB5009.4, GB5009.11, GB5009.12, GB5009.15, GB5009.17, GB4789.2, GB4789.15, GB4789.3, GB4789.4, and GB4789.10. Standard bulk packaging can be 25kg/drum, with customized packaging available. Residual solvent testing can be arranged according to buyer requirements, formulation standards, and third-party laboratory requests. With strict assay testing, heavy metal control, microbial testing, COA documentation, and third-party quality support, ProVita Biotech ensures its bulk Vitamin K2 MK-7 powder meets international quality expectations for supplement manufacturers, distributors, and private label brands.
Application
Bone Health Supplements
Vitamin K2 is widely used in bone support formulas because it helps activate osteocalcin, a key protein involved in calcium binding and bone mineralization. MK-7 and MK-4 are commonly added to capsules, tablets, softgels, and gummies for osteoporosis support, bone density maintenance, and healthy calcium metabolism.
Cardiovascular Health Formulas
Vitamin K2 supports vascular health by helping activate matrix Gla protein, which is associated with proper calcium utilization in the arteries. It is often used in heart health supplements, calcium balance formulas, and vitamin D3 + K2 products designed for cardiovascular wellness and arterial flexibility.
Functional Foods and Nutraceutical Products
Vitamin K2, especially menaquinone-7, is used in fortified foods, nutrition powders, dairy products, meal replacements, and private label supplements. Its long half-life, high activity, and compatibility with vitamin D, calcium, magnesium, and omega-3 formulas make it popular for daily wellness and healthy aging products.
Vitamin K2 MK-7 Powder Manufacturing Process
ProVita Biotech’s Vitamin K2 MK-7 Powder 99% is manufactured through a controlled production process designed to obtain high-purity menaquinone-7 powder for dietary supplements, softgels, capsules, tablets, and functional nutrition products. According to the flow chart, the process includes pre-treatment, pre-mixing with Vitamin K2 MK-7 oil, powder blending, final mixing, packaging, and finished product release.
1. Raw Material Pre-Treatment
The production starts with raw material inspection and pre-treatment. Vitamin K2 MK-7 oil and powder carriers are checked for identity, appearance, purity, moisture, contaminants, and compliance with internal quality standards. Only qualified raw materials are released for production.
2. Vitamin K2 MK-7 Oil Pre-Mixing
Vitamin K2 MK-7 oil is added into the pre-mixing stage to ensure uniform distribution before the main blending process. This step helps improve content uniformity, stability, and processing performance, which is especially important for high-purity MK-7 ingredients.
3. Powder Addition and Blending
After pre-mixing, selected powder materials are added and blended under controlled conditions. The purpose is to create a homogeneous Vitamin K2 MK-7 powder with consistent assay, particle distribution, and flowability for downstream supplement manufacturing.
4. Final Mixing and Homogenization
The material is further mixed to improve uniformity and reduce batch variation. During this stage, key parameters such as mixing time, temperature, humidity, and cross-contamination control are monitored to protect the activity and stability of menaquinone-7.
5. Quality Control Testing
Before release, the final Vitamin K2 MK-7 Powder 99% is tested for assay, purity, appearance, heavy metals, microbial limits, residual solvents, and other safety indicators. The finished powder is designed to meet international quality standards and can pass third-party testing for supplement manufacturers, distributors, and private label brands.
6. Packaging and Finished Product Release
After passing quality inspection, the Vitamin K2 MK-7 Powder 99% is packed in sealed, light-resistant packaging to protect it from oxygen, moisture, and light. Each batch can be supplied with COA, specification sheet, MSDS, and third-party test reports according to customer requirements.
ProVita Biotech controls the full manufacturing process from raw material inspection to final product release, ensuring high purity, stable quality, and reliable supply of Vitamin K2 MK-7 Powder 99% for global nutraceutical and dietary supplement customers.
Vitamin K2 MK-7 Benefits
- Supports bone health: Vitamin K2 MK-7 helps activate osteocalcin, a calcium-binding protein important for bone mineralization and bone density support.
- Promotes healthy calcium metabolism: MK-7 helps guide calcium into bones and teeth, supporting proper calcium utilization in the body.
- Supports cardiovascular wellness: Menaquinone-7 helps activate matrix Gla protein, which is related to calcium balance in blood vessels and arterial health.
- Works well with Vitamin D3: Vitamin D3 supports calcium absorption, while Vitamin K2 MK-7 helps direct calcium to the right places, making D3 + K2 formulas popular in supplements.
- Longer half-life than MK-4: MK-7 stays active in the body longer, making it suitable for once-daily dietary supplement products.
- Suitable for healthy aging formulas: Vitamin K2 MK-7 is commonly used in bone, heart, joint, calcium balance, and senior nutrition supplements.
- Popular in multiple dosage forms: Bulk Vitamin K2 MK-7 powder can be used in capsules, tablets, softgels, gummies, premixes, and functional nutrition products.
- Ideal for private label supplements: MK-7 powder is widely selected by supplement brands and OEM manufacturers for bone health, cardiovascular support, and Vitamin D3 combination formulas.
Where to Buy Bulk Vitamin K2 MK-7 Powder?
ProVita Biotech Co., Ltd. is a leading Vitamin K2 MK-7 powder supplier in China, offering high-purity bulk K2 MK-7 ingredients for dietary supplements, capsules, tablets, softgels, gummies, premixes, and functional nutrition formulas. As a reliable factory and wholesale manufacturer, we support supplement brands, ingredient distributors, contract manufacturers, and private label companies with stable quality, competitive pricing, and flexible OEM services.
Our bulk Vitamin K2 MK-7 powder is available in 99% pure powder and custom specifications, including microencapsulated powder, oil-based MK-7, and carrier-based formulations for different applications. Each batch can be supplied with COA, MSDS, specification sheet, third-party testing report, and related quality documents. GMP, Kosher, Halal, and other certificates are available according to product type and customer requirements.
| Advantage | ProVita Biotech Support |
|---|---|
| China Factory Supply | Direct bulk Vitamin K2 MK-7 powder from manufacturer |
| High Purity Option | 99% Vitamin K2 MK-7 powder available |
| Custom Formulas | MK-7 oil, powder, premix, microencapsulated forms |
| OEM Service | Capsules, tablets, softgels, gummies, and private label |
| Quality Control | Assay, heavy metals, residual solvents, microbiology testing |
| Documents | COA, MSDS, specification, third-party test reports |
| Certificate Support | GMP, Kosher, Halal, and export documents |
| Free Sample | Sample available for formulation and quality evaluation |
Contact ProVita Biotech today to get the latest wholesale price, free sample, specification sheet, and technical documents for bulk Vitamin K2 MK-7 powder.
FAQs
Vitamin K2 MK-7, also known as Menaquinone-7, is a fat-soluble vitamin K2 form widely used in bone health, cardiovascular wellness, calcium metabolism, and Vitamin D3 K2 supplement formulas. Compared with MK-4, MK-7 is popular because it has a longer half-life and is suitable for low-dose daily supplement products.
ProVita Biotech currently offers K2 MK-7 1.0% in MCC Powder and K2 MK-7 1.3% in MCC Powder. According to our COA, the 1.0% grade tested at 1.1% all-trans MK-7, and the 1.3% grade tested at 1.4% all-trans MK-7 by USP method. Custom specifications are also available for different supplement formulations.
MK-7 is usually fermentation-derived, commonly associated with natto fermentation, and is preferred for once-daily supplements because of its longer half-life. MK-4 is another Vitamin K2 form, often synthetic, and is commonly used in higher-dose or specific formulations. For most modern supplement brands, MK-7 is the more popular choice for capsules, tablets, softgels, gummies, drops, and D3 K2 formulas.
For daily dietary supplement products, MK-7 is generally considered the most efficient and commercially popular form because it works at microgram-level dosages and remains in circulation longer than MK-4. High-purity MK-7, all-trans MK-7, and stabilized MK-7 powder are especially valued by supplement manufacturers.
All-trans MK-7 refers to the active and preferred isomer form of Menaquinone-7. In Vitamin K2 sourcing, all-trans content is an important quality marker because it directly affects product potency, labeling accuracy, and formulation reliability. ProVita Biotech’s COA specifies Content of MK-7 (all-trans, %) for both 1.0% and 1.3% grades.
The CAS number of Vitamin K2 MK-7 is 2124-57-4. Other names include Menaquinone-7, Vitamin MK-7, Vitamin K2 MK-7, and all-trans MK-7.
Vitamin K2 MK-7 is a fat-soluble vitamin and is practically insoluble in water. For water-dispersible or powder-based supplement applications, it is usually processed with carriers, emulsification systems, or microencapsulation technology to improve handling and formulation compatibility.
Vitamin K2 MK-7 powder is widely used in bone health supplements, heart health formulas, Vitamin D3 K2 capsules, calcium magnesium K2 tablets, softgels, gummies, powder blends, women’s health supplements, healthy aging products, and private label nutrition formulas.
Vitamin D3 supports calcium absorption, while Vitamin K2 helps support normal calcium utilization. This makes D3 K2 supplements one of the most popular product formats in the bone health and cardiovascular wellness markets.
Yes. In addition to bulk Vitamin K2 MK-7 powder, ProVita Biotech offers OEM capsules, tablets, softgels, gummies, powder sachets, and custom D3 K2 formulas. We support supplement brands from raw material sourcing to finished product development.
Yes. ProVita Biotech can support private label Vitamin D3 K2 capsules, softgels, gummies, tablets, drops, and complex bone health formulas. Custom formula options can include calcium, magnesium, zinc, boron, collagen, vitamin D3, MK-7, and other functional nutrients.
Our Vitamin K2 MK-7 COA includes testing for appearance, odor, all-trans MK-7 assay, loss on drying, residue on ignition, heavy metals, arsenic, lead, cadmium, mercury, aerobic plate count, yeasts and molds, E. coli, Salmonella, and Staphylococcus aureus.
The specification controls heavy metals at ≤10 ppm, arsenic ≤0.5 ppm, lead ≤0.5 ppm, cadmium ≤0.3 ppm, and mercury ≤0.1 ppm. These limits help support quality and safety requirements for supplement manufacturers and distributors.
Yes. ProVita Biotech can provide COA, MSDS, specification sheet, product flow chart, third-party test report if required, packing list, invoice, and export documents. These documents help customers with supplier approval, quality review, customs clearance, and product development.
Yes. Third-party testing can be arranged according to buyer requirements. Common third-party test items include assay, all-trans MK-7 content, heavy metals, residual solvents, microbial limits, pesticides, allergens, and stability-related testing.
Standard packaging can be 1kg, 5kg, 10kg, or 25kg/drum, depending on order quantity and product specification. We can also provide customized packaging for trial orders, pilot production, and large-volume bulk supply.
ProVita Biotech is a professional bulk ingredient supplier and OEM supplement manufacturer in China. We provide Vitamin K2 MK-7 powder, custom specifications, COA and MSDS support, third-party testing, OEM capsules, tablets, softgels, gummies, private label formulas, international shipment, and formulation development for supplement brands, contract manufacturers, importers, and distributors.